Protein Alignment SLC22A2 and CG33234

DIOPT Version :9

• Sequence 1: NP_003049.2
• Gene: SLC22A2 / 6582
• HGNCID: 10966
• Length: 555
• Species: Homo sapiens
• Sequence 2: NP_001097483.2
• Gene: CG33234 / 2769006
• FlyBaseID: FBgn0053234
• Length: 475
• Species: Drosophila melanogaster
• Alignment Length: 432
• Identity: 97/432 - (22%)
• Similarity: 160/432 - (37%)
• Gaps: 85/432 - (19%)

Human   146 SWMLDLFQSSVNVGFFIGSMSIGYIADRFGRKLCLLTTVLINAAAGVLMAISPTYTWMLIFRLIQ 210
            :|::....::..|..|:.    |.:||.:||:..::.|..:.....:|.|..|.:...|..|.:.
  Fly    57 AWLMAASFAAQMVSCFLW----GELADVYGRRKIIMITSTVANIVSILSACVPEFWGFLFLRSVG 117

Human   211 GLVSKAGWLIGYILITEFVGRRYRRTVGIFYQVAYTVGLL---VLAGVAYAL----PHWRWLQFT 268
            |....|..:.....::||.....|..|......:..|.::   .||||...|    ..||.|...
  Fly   118 GFFIAASVVSLMTYLSEFTKISLRPRVLTIMSFSLGVSMIYVPCLAGVLLPLRTEPSSWRILLLC 182

Human   269 VSLPNFFFLLYYWCIPESPRWLISQNKNAEAMRIIKHIAKKNGKSLPASLQRLRLEEETGKKLNP 333
            ..:|....::....:||||::.:|.|...:||::::.|.:.| |....:|..|.:|..|..:|
  Fly   183 NQVPGIIGIIILVFLPESPKYYLSINNQEKAMQVMEKICRMN-KGKKVTLNSLGVESLTQPRL-- 244

Human   334 SFLDLVRTPQIRKH-----TMILMYN-----WFTSSVLYQGLIMHMGLAGDNIYLDFFYSALVEF 388
                  |.| ..||     |.:|:.|     ||.       .|:...|:|....|..:...:...
  Fly   245 ------RQP-TEKHGSCYETKVLLLNHAKIMWFF-------FIIFFSLSGLGFALPIWMLRVRVL 295

Human   389 PAAF---------MIILTIDRIGR-----RYPWAASNMVAGAACLASVFIPGD--LQWLK----- 432
            .|.|         :..:..|..||     .|......|:.|...|| :|:...  |.||.
  Fly   296 TATFTDWDTMCSHLDGIKADSPGRTECHLTYEQMTDPMIHGCVVLA-LFVVTSVILTWLSRRWVI 359

Human   433 ---IIISCLGRMGITMAYE--------------IVCLVN------AELYPTFIRNLGVHICSSMC 474
               |.||.:|.:.:.....              ::|.|.      .:|.||.:|.....:.|...
  Fly   360 IGYICISIIGCVALNFMEHPNLILISFFAIIDPLICSVRLAGSMLIDLVPTHLRGKVFALISMTG 424

Human   475 DIGGIITPFLV-YRLTNIWLELPLMVFGVLGLVAGGLVLLLP 515
            ..|.:||...| |.|:.| ..:...:|.::.:|.|..|..||
  Fly   425 RAGILITSVYVGYTLSYI-CYVTFNIFILVLIVTGCHVYWLP 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A2	NP_003049.2	2A0119	13..525	CDD:273328	97/432 (22%)
		MFS	124..492	CDD:119392	90/407 (22%)
CG33234	NP_001097483.2	MFS	56..>198	CDD:119392	30/144 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153346
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840