Protein Alignment SLC22A2 and CG33233

DIOPT Version :9

• Sequence 1: NP_003049.2
• Gene: SLC22A2 / 6582
• HGNCID: 10966
• Length: 555
• Species: Homo sapiens
• Sequence 2: NP_995978.2
• Gene: CG33233 / 2769005
• FlyBaseID: FBgn0053233
• Length: 489
• Species: Drosophila melanogaster
• Alignment Length: 471
• Identity: 99/471 - (21%)
• Similarity: 182/471 - (38%)
• Gaps: 93/471 - (19%)

Human   126 WVYETPGSSIVTEFNLVCANSWMLD-------LFQSSVNVGFFIGSMSIGYIADRFGRKLCLLTT 183
            ::|....:..:|...||...|...|       |..:|:..|.....:.||::|||:|||..:...
  Fly    28 FIYMYSVTESMTAGYLVVLTSCEFDTSPKEKTLLANSLLGGMVASGLFIGFLADRYGRKFVIRLA 92

Human   184 VLINAAAGVLMAISPTYTWMLIFRLIQG--LVSKAGWLIGYILITEFVGRRYRR-TVGIFYQ--- 242
            ::...:..|:.|:.|....:.:.|:|.|  |.:.|...:|:  :.||...::|. ||.|..|
  Fly    93 LVGALSFSVISALMPDLYSLSVIRIIVGTFLSAVASLQVGF--LGEFHAIKWRPITVAICSQSQG 155

Human   243 --VAY--TVGLLVL-------AGVAYALPHWRWLQFTVSLPNFFFLLYYWCIPESPRWLISQNKN 296
              :.|  .|.:.:|       ...:|.|..||:|.....:|.:..|:....:||:|.:|:|.|:.
  Fly   156 LALIYCPLVAMAILPNNFNVDLSSSYNLRVWRFLMMFFMIPGWLALVGICLVPETPHFLMSVNRP 220

Human   297 AEAMRIIKHIAKKNGK-----SLPASLQRLRLEEETG--KKLNPSFLDLVRTPQIRKH--TMILM 352
            .:|:..:|.|.:.|.|     .:..|.::....::.|  |.:...:..|...|.:.|.  .:.|:
  Fly   221 DKALLALKWICRMNRKKWEDVDITLSEEKSSTNDQEGFWKTVWYEYKLLFSKPHVFKFFICLFLI 285

Human   353 YNWFTSSV---LYQGLIMHMGLAGDNIYLDFFYSALVEFPAAFMIILTIDRIG--RRYPWAASNM 412
            :..|.:|:   ::..:|.:|..:|.|...|     ||.....|:.....|..|  ...|.....|
  Fly   286 FGIFFTSIGLGIWFPVIRNMDNSGSNRLCD-----LVNNNPTFINHEADDTNGTDSESPKCNDEM 345

Human   413 V------------AGAACLASVFIPGDLQW--------LKIIISCLGRMGIT---MAYEIVCL-- 452
            .            .|...||||.:    .|        |.|:||.:  :||:   |....|.|
  Fly   346 TNLIDPVYYGFTYIGCFILASVLV----HWMTRKYVIALHILISMI--LGISLNIMKQPTVVLIF 404

Human   453 -----------------VNAELYPTFIRNLGVHICSSMCDIGGIITPFLVYRLTNIWLELPLMVF 500
                             |..:..|..:|...:.:..|:...||::...::.....:..::...:|
  Fly   405 FVLMMVLPGVLIPLATSVLVDCLPVNLRGKALCMVRSLARFGGVLGSTMIGLFIRVTCDVTFNIF 469

Human   501 GVLGLVAGGLVLLLPE 516
            .:...:...|.:..|:
  Fly   470 NLCLAICVVLAVFQPK 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A2	NP_003049.2	2A0119	13..525	CDD:273328	99/471 (21%)
		MFS	124..492	CDD:119392	96/445 (22%)
CG33233	NP_995978.2	MFS_1	22..451	CDD:284993	96/435 (22%)
		MFS	23..>208	CDD:119392	43/181 (24%)
		MFS	354..>482	CDD:304372	23/133 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153345
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840