Protein Alignment SLC22A1 and CG31103

DIOPT Version :9

• Sequence 1: XP_005267159.1
• Gene: SLC22A1 / 6580
• HGNCID: 10963
• Length: 610
• Species: Homo sapiens
• Sequence 2: NP_001097914.1
• Gene: CG31103 / 43030
• FlyBaseID: FBgn0051103
• Length: 506
• Species: Drosophila melanogaster
• Alignment Length: 394
• Identity: 113/394 - (28%)
• Similarity: 159/394 - (40%)
• Gaps: 102/394 - (25%)

Human   167 GYFADRFGRKLCLL-GTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLV--SKGNWMAG-YTLITEF 227
            ||.:|..||:..|| |....||:..|||..:    |:.||.::..||  |.|...|. |..::||
  Fly    88 GYISDDIGRRRVLLYGNFASNALQFVLMFVT----SVWLFNIINLLVGISVGAVSAALYAYLSEF 148

Human   228 VGSGSRRTVAIMYQMAF----------TVGLV-----ALTGLAYALPHWRWLQLAVSLPTF---L 274
             .....|.|||.|...|          |..||     |:|...:....||.|.|...||.|   |
  Fly   149 -NIPRHRAVAINYSTMFVSVTAIYVPATAWLVLSSNWAITMGDFVFRPWRLLLLVSLLPGFIGGL 212

Human   275 FLLYYWCVPESPRWLLSQKRNTEAIKIMDHIAQKN-GK----LPPADLKMLSLEEDVTE------ 328
            .||||   ||||::||||::|.|||:.:..|::.| ||    :...|...|..|:.|.|
  Fly   213 ILLYY---PESPKFLLSQEKNNEAIEAVAWISKFNRGKSIQQVLSCDEFTLKSEDPVGENLLGES 274

Human   329 -------KLSPSFADLFRTPRLRKRTFIL--------------MYLWFTDSVLYQGLILHMGATS 372
                   |:..:...||..|  ....|||              |.|||.:.|....     ||.:
  Fly   275 QGCGILSKICRATIPLFHKP--HGFNFILCNLALFGMFFSSNGMQLWFPEIVNRSS-----GAEN 332

Human   373 GNLYLDFLYSALVEIPG----------------------AFIALITIDRVGRIY-PMAMSNLLAG 414
            .:..:..:.|..||.|.                      .|..||.....|.|. |:...|:|.
  Fly   333 NSSTVCEILSVPVEQPNVTETLDCTDPISSKTYIDNLVVGFAFLIGFSIQGLILNPLGRKNVLL- 396

Human   415 AACLVMIFISPDLHWLN-----IIIMCVGRM--GITIAIQMICLVNAELYPTFVRNLGVMVCSSL 472
            ||..|.......||::.     :::.|:..:  |::|:|.:..:|  :|.||.:|:..|..|.||
  Fly   397 AALAVATLSGVLLHFMESPTGVLVLFCLYILLPGLSISIMIGAIV--DLVPTHLRSKAVSFCMSL 459

Human   473 CDIG 476
            ..:|
  Fly   460 GRLG 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A1	XP_005267159.1	2A0119	12..499	CDD:273328	113/394 (29%)
		MFS	118..484	CDD:119392	113/394 (29%)
CG31103	NP_001097914.1	2A0115	29..475	CDD:273327	113/394 (29%)
		MFS	34..>189	CDD:119392	35/105 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153378
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840