Protein Alignment SLC22A1 and CG7084

DIOPT Version :10

• Sequence 1: XP_005267160.1
• Gene: SLC22A1 / 6580
• HGNCID: 10963
• Length: 573
• Species: Homo sapiens
• Sequence 2: NP_651016.1
• Gene: CG7084 / 42606
• FlyBaseID: FBgn0038938
• Length: 597
• Species: Drosophila melanogaster
• Alignment Length: 533
• Identity: 139/533 - (26%)
• Similarity: 226/533 - (42%)
• Gaps: 95/533 - (17%)

Human     4 VDD---------ILEQVGESGWFQK-QAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAEL 58
            |||         ::|:.|..|.:|. ..|:.:..|:.:.|.|.:.|:.....|||.|..||
  Fly    25 VDDSEFNDPFQALMEKAGNHGRYQTLYNFVFVGGLAFSGAMIYMNIILALNIPDHWCTVPG---- 85

Human    59 SQRCGWSPAEELNYTVPGLGP-AGEAFLGQCRRYEVD---------WNQSALSCVDPLASLATNR 113
            .:...:|..|..:.|:|.... .|......|..::::         ||.:.....:
  Fly    86 RENTNFSLEEWRDITLPKQADNRGRKTFSNCEMFQMNFSEITDWSAWNSNLTKTTE--------- 141

Human   114 SHLPLGPCQDGWVYDTP--GSSIVTEFNLVCADSWKLDLFQSCL----NAGFLFGSLGVGYFADR 172
                  .||:||.||..  .|:|.|:.|.|||.    |||.:.:    ....:.||..:|...|.
  Fly   142 ------ACQNGWSYDKTWYESTIPTDHNWVCAK----DLFVTNVFVVGRVTEVAGSFILGQMGDS 196

Human   173 FGRK--------LCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVG 229
            :||:        .|.||.:      |.:|..| :|...|:...:.||.....:.:...:..|...
  Fly   197 YGRRFVYYISVVFCSLGRL------GSIMCTS-SYTWFLIMSGIVGLTVNSLFQSPQIIGMEISR 254

Human   230 SGSRRTVAIMYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKR 294
            ...|..:|......:::|...:..|.:.|.||.......|:||.:.||:...|.||||||:|::|
  Fly   255 EEDRSRIAFFQSCGWSIGTTLMPLLYWWLRHWDSFMWLTSIPTAMVLLFSKYVIESPRWLISKQR 319

Human   295 NTEAIKIMDHIAQKNGKLPPADLKMLSLEEDVTEK------------LSPSFADLFRTPRLRKRT 347
            ..|||..:..||:.||.           ..|:|||            ::...|.||...||.:.|
  Fly   320 FREAIVQLQKIAKINGH-----------RFDMTEKELAEIYSRDKQDVTYGIASLFAGWRLARNT 373

Human   348 FILMYLWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLL 412
            .|:.:.|...:|.|..|:|.....:||.:|:|||.::||||...:.....|..||.:..::|.|:
  Fly   374 TIMGFSWCVVAVSYFTLVLFSSRMAGNPFLNFLYQSIVEIPAYVVGRYMGDTYGRRFTNSVSFLI 438

Human   413 AGAACLVMIFISPDLHWLNIIIMCVGRMGITIA-----IQMICLVNAELYPTFVRNLGVMVCSSL 472
            :...||.:|..|.|..:.|::|.....:....|     :.:.||   |:|||.:|..||.:.:.|
  Fly   439 SFVTCLPIIVYSTDERYENLMIYLATFIKFLNALTFFTVNLQCL---EIYPTCMRQTGVALGTIL 500

Human   473 CDIGGIITPFIVF 485
            .:..|::.|::|:
  Fly   501 ANAIGVLAPYLVY 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A1	XP_005267160.1	2A0119	12..500	CDD:273328	135/516 (26%)
CG7084	NP_651016.1	MFS_SLC22	146..542	CDD:340875	111/393 (28%)