Protein Alignment SLC22A1 and CG17752

DIOPT Version :10

• Sequence 1: XP_005267160.1
• Gene: SLC22A1 / 6580
• HGNCID: 10963
• Length: 573
• Species: Homo sapiens
• Sequence 2: NP_650817.1
• Gene: CG17752 / 42337
• FlyBaseID: FBgn0038718
• Length: 538
• Species: Drosophila melanogaster
• Alignment Length: 530
• Identity: 140/530 - (26%)
• Similarity: 227/530 - (42%)
• Gaps: 101/530 - (19%)

Human     7 ILEQVGESGWFQKQAFLILCLLSAAFAPICVGI-----VFLGFTPDHHCQSPGVAELSQRCGWSP 66
            :||:.|..|.:|     ||.|....:..|...:     ..:.|||.|.|.:| |.|.||
  Fly     6 VLEKCGNFGPYQ-----ILLLGLYGYTNIVSSLHYFSQTLISFTPSHRCSAP-VEEFSQ------ 58

Human    67 AEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGPCQDGWVYDTPG 131
                |:|        |.......:|:||           :.|...|:       | ..|.:|...
  Fly    59 ----NFT--------ELLSCSVIQYDVD-----------MTSFRDNK-------C-SSWDFDKES 92

Human   132 S--SIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGR-KLCLLGTVLVNAVSGVLM 193
            :  ||.||...||.|::||.:.||....|...||:..||.|||.|| ..|:|.|  :...||...
  Fly    93 NYESITTELEWVCDDAYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVLST--LTGASGDFF 155

Human   194 AFSPNYMSMLLF-RLLQGLVSKGNWMAGYTLITEFVGSGSRRT--VAIMYQMAFTVGLVALTGLA 255
            ......:.|..| |.:.||.....::..|.|:.|:: |...||  :.|:..:.:::||:....:|
  Fly   156 TSFVGSLPMFSFTRFISGLSMDTQYVLMYILVFEYL-SPQHRTFGLNIILGVFYSIGLMISPWIA 219

Human   256 YALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMDHIAQKNGKLPPADLKML 320
            ..|.:||....|.|||....|::...:.||..|||::.:..:|:..:..:|:.||:
  Fly   220 IWLGNWRSYLWAASLPALGMLIFPLFLHESVEWLLTKGKFDKAVNNLKSVAKFNGR--------- 275

Human   321 SLEEDV--------TEKL-------SPSFADLFRTPRLRKRTFILMYLWFTDSVLYQGLILHMGA 370
            .:|:.|        .|||       |.:|..:.|||||||.|.||:......::.:..|..::..
  Fly   276 QVEDSVFDEFIKHYREKLNSAQKKSSDTFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNVEG 340

Human   371 TSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVMIFISPDLHWL----- 430
            ...:.:..|.||..|.:||....::..:::|| ..||.::||.||      ||:....:|
  Fly   341 VGISPFKLFSYSGFVVLPGGLSIILFQNKIGR-KGMACASLLVGA------FITATTGYLVGTLD 398

Human   431 ----NIII---MCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLCDIGGIITPFIVFRLR 488
                ::::   :|:.|.|..:|........||:.||.||..||.....:.:.....:.:|:: |.
  Fly   399 PANYSVLLGFMVCLARFGAVVAYDAEAQYAAEIIPTSVRGRGVANIHVVGNAFAFFSSYIIY-LG 462

Human   489 EVWQALPLIL 498
            ..::.||.:|
  Fly   463 TFYKPLPSLL 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A1	XP_005267160.1	2A0119	12..500	CDD:273328	138/525 (26%)
CG17752	NP_650817.1	2A0119	11..498	CDD:273328	138/525 (26%)