Protein Alignment SLC22A1 and CG7333

DIOPT Version :9

• Sequence 1: XP_005267159.1
• Gene: SLC22A1 / 6580
• HGNCID: 10963
• Length: 610
• Species: Homo sapiens
• Sequence 2: NP_650814.2
• Gene: CG7333 / 42334
• FlyBaseID: FBgn0038715
• Length: 541
• Species: Drosophila melanogaster
• Alignment Length: 547
• Identity: 130/547 - (23%)
• Similarity: 221/547 - (40%)
• Gaps: 125/547 - (22%)

Human     7 ILEQVGESGWFQKQAFLILCLLSAAFAPICVGI-----VFLGFTPDHHCQSPGVAELSQRCGWSP 66
            :|::.|..|.||     ::.||...:..|...:     ..:.|||:|.|....:..||
  Fly     6 VLDKCGNYGRFQ-----VMILLLYGYTNILGSLHYFSQTLITFTPEHWCFHADLNGLS------- 58

Human    67 AEELNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSC------VDPLASLATNRSHLPLGPCQDGW 125
                   |.|:...          ||   |.||.||      |:....::|||.      |:: |
  Fly    59 -------VEGIRSV----------YE---NISASSCTPLLGVVNGTGVVSTNRK------CRN-W 96

Human   126 VYDTPG--SSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAV 188
            :::...  .||.||...||..|....:.||....|.:.|::..||.:|:.||...||...|..|.
  Fly    97 IFNRESGYESITTELKWVCDKSHHPAVGQSFFFMGSVVGTIIFGYLSDQVGRLPSLLMATLCGAT 161

Human   189 SGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRR-TVAIMYQMAFTVGLVALT 252
            ...:.:|..........|.:.||.:...:...|.|:.|::...||. .:.|:..:.:..||:...
  Fly   162 GDFITSFVHTLPWFAFSRFMSGLSTDTMYYLMYILVFEYLSPKSRTFGLNIILAVFYCFGLMTSP 226

Human   253 GLAYALPHWR---WLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMDHIAQKNGKLPP 314
            ..|..:.:||   ||   .|||....|:|.:.:.||.:|||::::..:|:..:..:|:.|.:
  Fly   227 WAAIWIGNWRRYLWL---ASLPALGVLIYPFLICESAQWLLTKRKYDDAVICLKKVAKFNRR--- 285

Human   315 ADLKMLSLEEDVTEKL-----------------SPSFADLFRTPRLRKRTFILMYLWFTDSVLYQ 362
                  .:||.|.::.                 ..:|..:|.|||||:         ||.::|.:
  Fly   286 ------HVEESVFDEFVKYYRERELQDYKLNSHEDTFLAMFLTPRLRR---------FTLTLLVK 335

Human   363 GLILHMGATSGNLYLD---------FLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAG---- 414
            .:|:.:.....|..::         |.::::|.:|.....|:..:::|| ..||.:.|..|
  Fly   336 SVIITLSCDVINRNMEGLGTSPFKLFSFTSIVYLPAGVAILLLQNKIGR-KGMACTALFVGGLIT 399

Human   415 -AACLVMIFISPDLHWLNIIIMC-VGRMGITIAIQMICLVNAELYPTFVRNLGV-------MVCS 470
             |...::..:.|..:.|.:.||. :||.|.|::........||:.||.||...|       :..|
  Fly   400 TATGFMIAHLDPTENALLLAIMVGLGRFGATVSYDAEIQYAAEIIPTSVRGQAVSNIHVIGLASS 464

Human   471 SLCDIGGIITPFIVFRLREVWQALPLI 497
            ||.        |.|..|.:.::.||.|
  Fly   465 SLA--------FYVIYLAQYYKPLPSI 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A1	XP_005267159.1	2A0119	12..499	CDD:273328	129/542 (24%)
		MFS	118..484	CDD:119392	97/410 (24%)
CG7333	NP_650814.2	2A0119	11..510	CDD:273328	129/542 (24%)
		MFS	126..499	CDD:119392	92/388 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153741
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.950