Protein Alignment SLC22A1 and CG14857

DIOPT Version :10

• Sequence 1: XP_005267160.1
• Gene: SLC22A1 / 6580
• HGNCID: 10963
• Length: 573
• Species: Homo sapiens
• Sequence 2: NP_650392.1
• Gene: CG14857 / 41791
• FlyBaseID: FBgn0038262
• Length: 560
• Species: Drosophila melanogaster
• Alignment Length: 513
• Identity: 125/513 - (24%)
• Similarity: 216/513 - (42%)
• Gaps: 51/513 - (9%)

Human     5 DDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHCQSPGVAELSQRCGWSPAEE 69
            |.|||:.|.:|.:|....|:|..::............:||.|.|.|....:...|       .||
  Fly     4 DQILEKCGSAGRYQYLMILLLGYIAFTTTVHYYSQNIIGFVPQHWCYHEALENRS-------FEE 61

Human    70 LNYTVPGLGPAGEAFLGQCRRYEVDWNQSALSCVDPLASLATNRSHLPLGPCQDGWV--YDTPGS 132
            :   .....|.|:.  ..|.|               |..:..:|..:....|| .|:  ||....
  Fly    62 I---AAIYAPFGKE--ASCTR---------------LDKIEGDRVTVSNETCQ-RWIYNYDFGFR 105

Human   133 SIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNA---VSGVLMA 194
            |:..|.|.||.|::|..:.||....|.|.|:...|...||.||   :...:|.|.   |...|..
  Fly   106 SMNAELNWVCNDAYKARIGQSLFFLGSLMGTFTFGVLGDRIGR---VRAVILANQCGFVGDFLTT 167

Human   195 FSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAI--MYQMAFTVGLVALTGLAYA 257
            ::.|.:...:||.:.||.:..|:...:.|:.|:: :...|.:||  ...:.|.:|.:....|:..
  Fly   168 YASNLVQFAIFRCISGLAATANYYLMFILVLEYL-APKLRNMAISGTLGICFCLGALVAPWLSVL 231

Human   258 LPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMDHIAQKNG-KLPPADLKMLS 321
            ..:||......:|...:..|:|:.|.||.:||:::.....||..:.|||..|| ::..||.:...
  Fly   232 AGNWRIYLTCSALLQLVVALFYFVVQESAQWLITRTNVEGAIARLKHIAHFNGMEVKAADFEAFR 296

Human   322 LEEDVTEKLS------PSFADLFRTPRLRKRTFILMYLWFTDSVLYQGLILHMGATSGNLYLDFL 380
            ....|..|||      ....||.|||.|||.:.::::.:...|:.:..:..::.....:.::.|.
  Fly   297 RNCIVKRKLSNQPEQTAGIFDLLRTPNLRKVSLLVVFTFMLTSLSFNTISRNVEGMGLSPFVVFS 361

Human   381 YSALVEIPGAFIALITIDRVGRIYPMAMSNLLAG-AACLVMIFISPDLHWLNIIIMCV----GRM 440
            ..|:|..|..||..:...||||.....::.|..| .:|.:.:.:|.:....|:.::..    .|:
  Fly   362 LFAVVVPPSGFIQGLLQSRVGRKATAFLAMLCTGLLSCALGVALSTEGAQKNVTLLLAFALPMRL 426

Human   441 GITIAIQMICLVNAELYPTFVRNLGVMVCSSLCDIGGIITPFIVFRLREVWQALPLIL 498
            ||::...:.....:||.||.||:.|:............::|:::....::..|..|||
  Fly   427 GISMCYTVTSQFASELLPTCVRSRGIAAVHLAAAGASFVSPYLIHLGTKLAAAPSLIL 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A1	XP_005267160.1	2A0119	12..500	CDD:273328	121/506 (24%)
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	121/506 (24%)