Protein Alignment SLC22A1 and CG4324

DIOPT Version :10

• Sequence 1: XP_005267160.1
• Gene: SLC22A1 / 6580
• HGNCID: 10963
• Length: 573
• Species: Homo sapiens
• Sequence 2: NP_611868.1
• Gene: CG4324 / 37830
• FlyBaseID: FBgn0034956
• Length: 478
• Species: Drosophila melanogaster
• Alignment Length: 408
• Identity: 103/408 - (25%)
• Similarity: 177/408 - (43%)
• Gaps: 67/408 - (16%)

Human   116 LPLGPCQDGWVYDTPGSSIVTEF--NLVCADSWKLDLFQ--SCLNAGFLFGSLGVGYF---ADRF 173
            |.:|.|   |:.|:...:|::..  :|.|  .|.:..||  |.....||...|...::   ::|:
  Fly    60 LLVGLC---WMSDSMEMAILSILGPSLFC--EWNVTKFQQASVTTVVFLGMMLSSSFWTQLSNRY 119

Human   174 GRK--LCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTV 236
            |||  |.|.|.:||  :..:|.:.:|:|..:|..|.|.|. :.|......||..||:.:..:...
  Fly   120 GRKSALTLFGVLLV--LYSILSSVAPSYAWLLTLRGLVGF-AIGCVPQSVTLYAEFLPTKHKGKC 181

Human   237 AIMYQMAFTVGL---VALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEA 298
            .::....:.:|.   |.|..:.|....||.|....:.|..:|.:....:.||.|:......|.:|
  Fly   182 VVLMDCFWALGACFEVVLALVVYPYYGWRGLLALSATPLLIFTILSPWLSESARYYSYNGHNDKA 246

Human   299 IKIMDHIAQKN------GKLPPADLKMLSLEEDVTEKLSPSFADLFR---TPRLRKRTFILMYLW 354
            ||:::.||..|      |:|...|              .||.|:.||   :|.|.:.|.:|.:||
  Fly   247 IKVLEQIAHNNKRHMLMGRLMADD--------------EPSCAESFRSLLSPSLYRTTILLWFLW 297

Human   355 FTDSVLYQGLILHMGATSGNL-------------------YLDFLYSALVEIPGAFIALITIDRV 400
            ...:..|.||:|   .|:..|                   ::|.|:..|.|.||..:.:..:...
  Fly   298 LASAFCYYGLVL---VTTELLVARNKESHPNECVTFMTSDFMDLLWITLSEFPGILLTIKVVKLF 359

Human   401 GRIYPMAMSNLLAGAACLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLG 465
            |:...:.: ..||...| .::.:|.:..:...:.:.:.|..|:...|.|.:...|:||..:|::|
  Fly   360 GKKKTIVL-QYLALVLC-TLVLMSVESRFSTSVTLFIARGTISGIFQAIYVYTPEIYPAALRSVG 422

Human   466 VMVCSSLCDIGGIITPFI 483
            |..||.|..:|.::|||:
  Fly   423 VSGCSVLARLGAMLTPFV 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A1	XP_005267160.1	2A0119	12..500	CDD:273328	103/408 (25%)
CG4324	NP_611868.1	MFS	59..471	CDD:475125	103/408 (25%)