Protein Alignment SLC22A1 and Balat

DIOPT Version :10

• Sequence 1: XP_005267160.1
• Gene: SLC22A1 / 6580
• HGNCID: 10963
• Length: 573
• Species: Homo sapiens
• Sequence 2: NP_610823.1
• Gene: Balat / 36417
• FlyBaseID: FBgn0033778
• Length: 604
• Species: Drosophila melanogaster
• Alignment Length: 540
• Identity: 158/540 - (29%)
• Similarity: 256/540 - (47%)
• Gaps: 77/540 - (14%)

Human     5 DDILEQVGESGWFQKQAFLILC--LLSAAFAPICV----GIVFLGFTPDHHCQSPGVAELSQRCG 63
            |::|.:||..|.:||   :|:|  ||.||..  |.    ..:|:..||.|.|:.|.:...:|
  Fly     4 DEVLREVGSFGLYQK---VIICSVLLPAALP--CAFHAYSQLFIAATPQHFCRVPELEPWTQ--- 60

Human    64 WSPAEEL--NYTVPGLGPAGEAFLGQCRRYEVDW----------------NQSALSCVDPLASLA 110
              ...:|  |.::|.......|   :|..|..::                .|.|    :.|..|.
  Fly    61 --DYVQLVKNLSIPRNRNGAYA---ECSMYSRNYTDIVRYLEYRPPPDLLRQQA----EDLLKLQ 116

Human   111 TNRSHLPLGPCQDGWVYDTP--GSSIVTEFNLVCADSWKLDLFQSCLNAGFLFGSLGVGYFADRF 173
            .:.:.:.  |||.||.||..  .|::|.|:||||..|:.:.|.......|.|.|:...||..|.:
  Fly   117 PDTTQVV--PCQHGWHYDKSIYSSTVVQEWNLVCDRSFLVTLALVVFGVGGLLGNYVFGYLVDLW 179

Human   174 GRKLCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAI 238
            ||:......:|:..::....||:.||.:.|..|.:.||.......:.|.|..|.||...|....|
  Fly   180 GRRPSFYAYLLLEIIACAASAFAWNYYTWLGLRFVVGLTVPAILASPYVLAIELVGPERRVFCTI 244

Human   239 MYQMAFTVGLVALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMD 303
            :..:|:::|||.|.|:.|.:..||.|.||||:|..:....::.:|||||||::..:...||||:.
  Fly   245 VSNIAYSLGLVVLAGVIYIVRDWRELSLAVSMPLLMLFSCFFVLPESPRWLMAVGKTRRAIKILK 309

Human   304 HIAQKNGKLPPADLKMLSLEEDVTEKLSPSFA------------------DLFRTPRLRKRTFIL 350
            .:|:.||         :.:..|..|:|.....                  ||||.|.:|::|.|:
  Fly   310 VMARVNG---------VRVNRDFVERLQRKLVITRAAETKSSMTTHYGILDLFRGPNMRRKTLII 365

Human   351 MYLWFTDSVLYQGLILHMGATSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGA 415
            ..:||.::.:|.||..:..|..|:...:|..:..||:|...:....:...||.:.:.:|.|:.|.
  Fly   366 TLIWFANTSVYVGLSYYAPALGGDEIWNFFLAGAVELPTYLLLWPGLSYFGRRWILFISMLVGGV 430

Human   416 ACLVMIFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLCDIGGIIT 480
            || |..|:.||   :.:::.|||:|||:.:..::.|:.:|||||.||.||:...|.:..:|.|:.
  Fly   431 AC-VATFLYPD---ITLLLYCVGKMGISSSFVVLPLMASELYPTVVRGLGMSFSSVISMVGPIVI 491

Human   481 PFIVFRLREVWQALPLILFG 500
            | ::..:.:....||||:.|
  Fly   492 P-MINHMGQQMLVLPLIVMG 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A1	XP_005267160.1	2A0119	12..500	CDD:273328	154/531 (29%)
Balat	NP_610823.1	MFS_SLC22	128..524	CDD:340875	124/397 (31%)