Protein Alignment SLC22A1 and CG31106

DIOPT Version :10

• Sequence 1: XP_005267160.1
• Gene: SLC22A1 / 6580
• HGNCID: 10963
• Length: 573
• Species: Homo sapiens
• Sequence 2: NP_733086.2
• Gene: CG31106 / 318594
• FlyBaseID: FBgn0051106
• Length: 513
• Species: Drosophila melanogaster
• Alignment Length: 462
• Identity: 106/462 - (22%)
• Similarity: 175/462 - (37%)
• Gaps: 106/462 - (22%)

Human   126 VYDTPGSSIVT-----EFNLVCADSWKLDLFQSCLNA----GFLFGSLGVGYFADRFGRKLCLLG 181
            :.:|.|.|.:|     :|.:...|       ::.::|    |....|...||.:|..||:..|:.
  Fly    54 INETMGMSYITIVSQCDFEMNSMD-------KAVMSAASFIGIFCSSYFWGYLSDTIGRRPVLIY 111

Human   182 TVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQMAFTV 246
            |.:......:.....|||...:..|...|....|.....|..:.||. :...|.:||.|...| |
  Fly   112 TTIAGNFLSLCSTVIPNYWLYVFIRFGVGFFIAGASSTTYAYLGEFF-TPRHRPIAINYASLF-V 174

Human   247 GL------------------VALTGLAYALPHWRWLQLAVSLPTFLFLLYYWCVPESPRWLLSQK 293
            |:                  |::|. .::|..||.|.:...||..:..|..|.:||||:.|:|..
  Fly   175 GVSTVYVPATAWLILSMDWSVSITD-GFSLRPWRLLTICYLLPGVVGTLMLWSLPESPKILMSLH 238

Human   294 RNTEAIKIMDHIAQKNG----------KLPPAD------LKMLSLEEDVT-EKLSPSFADLFRTP 341
            :..||...:|.||..|.          ||...|      :.::|.....| :|:......|.|.|
  Fly   239 KTEEAFAAVDWIAVTNSGKHLHEFKVHKLKTEDNANGENILLISKSAFTTIKKMWKETLPLLRRP 303

Human   342 RLRKRTFIL--------------MYLWF------------TDSV----LYQGLILHMGATSGN-- 374
            .|  ..|::              |.||:            .||:    :....|..|.|.:.|
  Fly   304 HL--LNFVISCTIMCGLFFSSSGMGLWYPEIQNRLGSNAADDSMTVCQVIDASIDQMQANASNKI 366

Human   375 --------LYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVMIFISPDLHWLN 431
                    .|:|.:......|.|..:..:.|:.:||...:::...||||..:.:|||..::
  Fly   367 CDDHINTKSYIDTITYGSALIVGYILMGLVINTIGRKASISIGLTLAGACAIALIFIKDEV---- 427

Human   432 IIIMC----VGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSSLCDIGGIITPFIVFRLREVWQ 492
            .|::|    :...|:.::|....:|  :|.||.:|...|.:|..|...|.:....|:..|.|.:.
  Fly   428 AIVVCFCLYLVLPGLCVSILSGAVV--DLVPTHLRGKAVCICLMLGRTGSVFGSNIIGVLLESYC 490

Human   493 ALPLILF 499
            :|...:|
  Fly   491 SLTFGVF 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A1	XP_005267160.1	2A0119	12..500	CDD:273328	106/462 (23%)
CG31106	NP_733086.2	synapt_SV2	11..>338	CDD:130366	68/295 (23%)
		MFS	<400..510	CDD:475125	27/104 (26%)