Protein Alignment SLC22A1 and CG3690

DIOPT Version :10

• Sequence 1: XP_005267160.1
• Gene: SLC22A1 / 6580
• HGNCID: 10963
• Length: 573
• Species: Homo sapiens
• Sequence 2: NP_569876.3
• Gene: CG3690 / 31047
• FlyBaseID: FBgn0040350
• Length: 558
• Species: Drosophila melanogaster
• Alignment Length: 460
• Identity: 96/460 - (20%)
• Similarity: 170/460 - (36%)
• Gaps: 159/460 - (34%)

Human   120 PCQDGWVYDTPGSSIV---TEFNLVCADSWKLDLF-QSCLN----AGFLFGSLGVGYFADRFGRK 176
            |...|.||:|...|.:   .|.:|      ||.|. :..||    ||.:..::..||.||..||:
  Fly    54 PAAMGTVYETSTMSYILPSAECDL------KLSLLDKGILNAITYAGMISSAVLWGYLADIKGRR 112

Human   177 -----------LCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGNWMAGYTLITEFVGS 230
                       :|:||.           |.|.:.:.:::|:.|.|....|.:....|.:||..|.
  Fly   113 NLLIVGYAADTICVLGG-----------ALSQSRIQLMVFKYLGGFCMSGPFAVLMTYLTELHGR 166

Human   231 GSRRTVAIMYQMAFTVGLVALTGLA--------------YALPHWRWLQLAVSLPTFLFLLYYWC 281
            ..|:.:.:|..:.|::..:.|.|||              .:|..|::.....:||:.|..:.::.
  Fly   167 KHRQRIMMMVGIMFSIATLTLPGLAMLILPETWNIQIWTLSLTSWQFFVAVTALPSLLSFVLFFF 231

Human   282 VPESPRWLLSQKRNTEAI---KIMDHIAQKNGK-------------LP----------PADLKML 320
            .||||::|:|:.||.||:   |.|.|:..:..|             :|          |.:||
  Fly   232 FPESPKFLMSKGRNREALDAFKFMYHLNSRKPKDSFPIKLLANEVIVPVKKHAKDETIPTELK-- 294

Human   321 SLEEDVTEKLSPSFAD---------------LFRTPRLRKRTFILMYLWFTDSVLYQGLILHMGA 370
             |..:..|...|...|               ||..|      ::.:.||    |......:.:|.
  Fly   295 -LPTECVEVQDPENQDSKKSSLRSGFTQLRPLFTKP------YLGLSLW----VYLLNFCVLLGQ 348

Human   371 TSGNLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAG-----AACLVM---------- 420
            .:..|:|..|::::.|                     ..||::|     :.|.::
  Fly   349 NTMRLWLPQLFASINE---------------------YENLMSGESQSTSICNILEYSVNRTQSQ 392

Human   421 --------------IFISPDLHWLNIIIMCVGRMGITIAIQMICLVNAELYPTFVRNLGVMVCSS 471
                          :.|:|..:..|:|:...|.:...:|..::.||..:|    :...|:::.:.
  Fly   393 LEAVTRNDPTVECHVIITPSTYTNNLIVAGAGFVAYMLAGFLVNLVGVKL----IMTSGLLIAAG 453

Human   472 LCDIG 476
             |.||
  Fly   454 -CSIG 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC22A1	XP_005267160.1	2A0119	12..500	CDD:273328	96/460 (21%)
CG3690	NP_569876.3	synapt_SV2	25..550	CDD:130366	96/460 (21%)