DRSC/TRiP Functional Genomics Resources

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Protein Alignment SLC22A1 and CG33234

DIOPT Version :10

Sequence 1:XP_005267160.1 Gene:SLC22A1 / 6580 HGNCID:10963 Length:573 Species:Homo sapiens
Sequence 2:NP_001097483.2 Gene:CG33234 / 2769006 FlyBaseID:FBgn0053234 Length:475 Species:Drosophila melanogaster


Alignment Length:441 Identity:99/441 - (22%)
Similarity:163/441 - (36%) Gaps:123/441 - (27%)


- Green bases have known domain annotations that are detailed below.


Human   153 SCLNAGFLFGSLGVGYFADRFG-RKLCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLLQGLVSKGN 216
            ||    ||:|.|     ||.:| ||:.::.:.:.|.|| :|.|..|.:...|..|.:.|.....:
  Fly    70 SC----FLWGEL-----ADVYGRRKIIMITSTVANIVS-ILSACVPEFWGFLFLRSVGGFFIAAS 124

Human   217 WMAGYTLITEFVGSGSRRTVAIMYQMAFTVGLVALTGLAYAL-------PHWRWLQLAVSLPTFL 274
            .::..|.::||.....|..|..:...:..|.::.:..||..|       ..||.|.|...:|..:
  Fly   125 VVSLMTYLSEFTKISLRPRVLTIMSFSLGVSMIYVPCLAGVLLPLRTEPSSWRILLLCNQVPGII 189

Human   275 FLLYYWCVPESPRWLLSQKRNTEAIKIMDHIAQKN-GKLPPADLKMLSLEEDVTEKLSPSFADLF 338
            .::....:||||::.||.....:|:::|:.|.:.| ||  ...|..|.: |.:|:          
  Fly   190 GIIILVFLPESPKYYLSINNQEKAMQVMEKICRMNKGK--KVTLNSLGV-ESLTQ---------- 241

Human   339 RTPRLRK---------RTFILM-----YLWFTDSVLY--QGL------------ILHMGATSGNL 375
              ||||:         .|.:|:     .:||...:.:  .||            :|....|..:.
  Fly   242 --PRLRQPTEKHGSCYETKVLLLNHAKIMWFFFIIFFSLSGLGFALPIWMLRVRVLTATFTDWDT 304

Human   376 YLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVMIFI-SPDLHWLN---III-- 434
            ....|.....:.||.....:|       |......::.|...|.:..: |..|.||:   :||  
  Fly   305 MCSHLDGIKADSPGRTECHLT-------YEQMTDPMIHGCVVLALFVVTSVILTWLSRRWVIIGY 362

Human   435 MCVGRMG-----------------ITIAIQMICLVN------AELYPTFVRNLGVMVCSSLCDIG 476
            :|:..:|                 ..|...:||.|.      .:|.||.:|.....:.|.....|
  Fly   363 ICISIIGCVALNFMEHPNLILISFFAIIDPLICSVRLAGSMLIDLVPTHLRGKVFALISMTGRAG 427

Human   477 GIITP-----------FIVFRLREVWQALPLILFG----------QRTSKT 506
            .:||.           ::.|.:    ..|.||:.|          ||||.|
  Fly   428 ILITSVYVGYTLSYICYVTFNI----FILVLIVTGCHVYWLPSEFQRTSFT 474

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SLC22A1XP_005267160.1 2A0119 12..500 CDD:273328 93/423 (22%)
CG33234NP_001097483.2 2A0119 <64..>234 CDD:273328 47/175 (27%)

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