Protein Alignment BMPR1B and bmpr1b

DIOPT Version :10

• Sequence 1: NP_001243722.1
• Gene: BMPR1B / 658
• HGNCID: 1077
• Length: 532
• Species: Homo sapiens
• Sequence 2: NP_001072633.1
• Gene: bmpr1b / 780089
• XenbaseID: XB-GENE-483455
• Length: 532
• Species: Xenopus tropicalis
• Alignment Length: 532
• Identity: 476/532 - (89%)
• Similarity: 507/532 - (95%)
• Gaps: 0/532 - (0%)

Human     1 MGWLEELNWQLHIFLLILLSMHTRANFLDNMLLRSAGKLNVGTKKEDGESTAPTPRPKVLRCKCH 65
            |||:||.|||||:.|::|||:|||||.||||||||:.||||.::|||.|||||.|..|:|.|.||
 Frog     1 MGWMEERNWQLHVSLIMLLSLHTRANLLDNMLLRSSAKLNVDSRKEDTESTAPAPPQKMLACYCH 65

Human    66 HHCPEDSVNNICSTDGYCFTMIEEDDSGLPVVTSGCLGLEGSDFQCRDTPIPHQRRSIECCTERN 130
            |||||||.||.|.|||||||::|||:||||||||||||||||||||||||||||||||||||:.:
 Frog    66 HHCPEDSFNNTCWTDGYCFTIVEEDESGLPVVTSGCLGLEGSDFQCRDTPIPHQRRSIECCTDED 130

Human   131 ECNKDLHPTLPPLKNRDFVDGPIHHRALLISVTVCSLLLVLIILFCYFRYKRQETRPRYSIGLEQ 195
            .||:||||||||||..|||||.||:.||||||||||::|.:|::||||||||||.|||||||:||
 Frog   131 FCNRDLHPTLPPLKKPDFVDGSIHYMALLISVTVCSIILAIILIFCYFRYKRQEARPRYSIGIEQ 195

Human   196 DETYIPPGESLRDLIEQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAV 260
            |||||||||||:|||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   196 DETYIPPGESLKDLIEQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAV 260

Human   261 KVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTT 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   261 KVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTT 325

Human   326 LDAKSMLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISD 390
            ||.|:|||||||:||||||||||||.|:|||||||||||||||||||||||||||||||||||||
 Frog   326 LDTKAMLKLAYSTVSGLCHLHTEIFGTKGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISD 390

Human   391 TNEVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEVARRCVSGGIVEEYQL 455
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||:||||:|||||
 Frog   391 TNEVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEVARRCISGGILEEYQL 455

Human   456 PYHDLVPSDPSYEDMREIVCIKKLRPSFPNRWSSDECLRQMGKLMTECWAHNPASRLTALRVKKT 520
            ||||:||||||||||||||||::.|||||||||||||||||||||||||||||||||||||||||
 Frog   456 PYHDVVPSDPSYEDMREIVCIRRFRPSFPNRWSSDECLRQMGKLMTECWAHNPASRLTALRVKKT 520

Human   521 LAKMSESQDIKL 532
            ||||||||||||
 Frog   521 LAKMSESQDIKL 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BMPR1B	NP_001243722.1	TFP_LU_ECD_BMPR1B	58..143	CDD:467133	70/84 (83%)
		STKc_BMPR1b	228..532	CDD:271121	292/303 (96%)
bmpr1b	NP_001072633.1	TFP_LU_ECD_BMPR1B	58..143	CDD:467133	70/84 (83%)
		TGF_beta_GS	205..232	CDD:462503	25/26 (96%)
		Protein Kinases, catalytic domain	228..532	CDD:473864	292/303 (96%)