Protein Alignment BMPR1B and bmpr1b

DIOPT Version :9

• Sequence 1: NP_001243722.1
• Gene: BMPR1B / 658
• HGNCID: 1077
• Length: 532
• Species: Homo sapiens
• Sequence 2: NP_001072633.1
• Gene: bmpr1b / 780089
• XenbaseID: XB-GENE-483455
• Length: 532
• Species: Xenopus tropicalis
• Alignment Length: 532
• Identity: 476/532 - (89%)
• Similarity: 507/532 - (95%)
• Gaps: 0/532 - (0%)

Human     1 MGWLEELNWQLHIFLLILLSMHTRANFLDNMLLRSAGKLNVGTKKEDGESTAPTPRPKVLRCKCH 65
            |||:||.|||||:.|::|||:|||||.||||||||:.||||.::|||.|||||.|..|:|.|.||
 Frog     1 MGWMEERNWQLHVSLIMLLSLHTRANLLDNMLLRSSAKLNVDSRKEDTESTAPAPPQKMLACYCH 65

Human    66 HHCPEDSVNNICSTDGYCFTMIEEDDSGLPVVTSGCLGLEGSDFQCRDTPIPHQRRSIECCTERN 130
            |||||||.||.|.|||||||::|||:||||||||||||||||||||||||||||||||||||:.:
 Frog    66 HHCPEDSFNNTCWTDGYCFTIVEEDESGLPVVTSGCLGLEGSDFQCRDTPIPHQRRSIECCTDED 130

Human   131 ECNKDLHPTLPPLKNRDFVDGPIHHRALLISVTVCSLLLVLIILFCYFRYKRQETRPRYSIGLEQ 195
            .||:||||||||||..|||||.||:.||||||||||::|.:|::||||||||||.|||||||:||
 Frog   131 FCNRDLHPTLPPLKKPDFVDGSIHYMALLISVTVCSIILAIILIFCYFRYKRQEARPRYSIGIEQ 195

Human   196 DETYIPPGESLRDLIEQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAV 260
            |||||||||||:|||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   196 DETYIPPGESLKDLIEQSQSSGSGSGLPLLVQRTIAKQIQMVKQIGKGRYGEVWMGKWRGEKVAV 260

Human   261 KVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTT 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   261 KVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDYLKSTT 325

Human   326 LDAKSMLKLAYSSVSGLCHLHTEIFSTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISD 390
            ||.|:|||||||:||||||||||||.|:|||||||||||||||||||||||||||||||||||||
 Frog   326 LDTKAMLKLAYSTVSGLCHLHTEIFGTKGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVKFISD 390

Human   391 TNEVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEVARRCVSGGIVEEYQL 455
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||:||||:|||||
 Frog   391 TNEVDIPPNTRVGTKRYMPPEVLDESLNRNHFQSYIMADMYSFGLILWEVARRCISGGILEEYQL 455

Human   456 PYHDLVPSDPSYEDMREIVCIKKLRPSFPNRWSSDECLRQMGKLMTECWAHNPASRLTALRVKKT 520
            ||||:||||||||||||||||::.|||||||||||||||||||||||||||||||||||||||||
 Frog   456 PYHDVVPSDPSYEDMREIVCIRRFRPSFPNRWSSDECLRQMGKLMTECWAHNPASRLTALRVKKT 520

Human   521 LAKMSESQDIKL 532
            ||||||||||||
 Frog   521 LAKMSESQDIKL 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BMPR1B	NP_001243722.1	Activin_recp	60..140	CDD:279413	66/79 (84%)
		STKc_BMPR1b	228..532	CDD:271121	292/303 (96%)
		S_TKc	235..519	CDD:214567	272/283 (96%)
bmpr1b	NP_001072633.1	Activin_recp	64..136	CDD:395845	60/71 (85%)
		TGF_beta_GS	205..232	CDD:400699	25/26 (96%)
		STKc_BMPR1b	228..532	CDD:271121	292/303 (96%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	579	1.000	Domainoid score	I2650
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H20322
Inparanoid	1	1.050	955	1.000	Inparanoid score	I3344
NCBI	1	1.000	-	-
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D100898at32523
OrthoFinder	1	1.000	-	-		FOG0000203
OrthoInspector	1	1.000	-	-		oto155594
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2798
SonicParanoid	1	1.000	-	-		X151
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	10.090