Protein Alignment SLC25A1 and sea

DIOPT Version :9

• Sequence 1: NP_001243463.1
• Gene: SLC25A1 / 6576
• HGNCID: 10979
• Length: 318
• Species: Homo sapiens
• Sequence 2: NP_001027175.1
• Gene: sea / 3772221
• FlyBaseID: FBgn0037912
• Length: 317
• Species: Drosophila melanogaster
• Alignment Length: 305
• Identity: 196/305 - (64%)
• Similarity: 237/305 - (77%)
• Gaps: 10/305 - (3%)

Human    21 PERQRP------GGSLRSG----FPVPAGGLAGGIEICITFPTEYVKTQLQLDERSHPPRYRGIG 75
            |.|:||      ..:..||    ..:.|||:.||||||||:|||||||||||||:....:|.||.
  Fly    12 PYRRRPWMTEHGAAAADSGQVGLKGIVAGGITGGIEICITYPTEYVKTQLQLDEKGAAKKYNGIF 76

Human    76 DCVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFEFLSNHMRDAQGRLDSTRGLLCGLGAGV 140
            |||::||...|.||||||||.|:||||||:|.|||.||||.::..|::|:|.::..|||||||||
  Fly    77 DCVKKTVGERGFLGLYRGLSVLVYGSIPKSAARFGAFEFLKSNAVDSRGQLSNSGKLLCGLGAGV 141

Human   141 AEAVVVVCPMETIKVKFIHDQTSPNPKYRGFFHGVREIVREQGLKGTYQGLTATVLKQGSNQAIR 205
            .||:|.|.||||||||||:||.|.|||:|||.|||.:|::.:|:.|.|:|||.|:||||||||||
  Fly   142 CEAIVAVTPMETIKVKFINDQRSGNPKFRGFAHGVGQIIKSEGISGIYKGLTPTILKQGSNQAIR 206

Human   206 FFVMTSLRNWYRGDNPNKPMNPLITGVFGAIAGAASVFGNTPLDVIKTRMQGLEAHKYRNTWDCG 270
            |||:.||::.|:||:..||:..|:.||||||||||||||||||||:|||||||||.||:||..|.
  Fly   207 FFVLESLKDLYKGDDHTKPVPKLVVGVFGAIAGAASVFGNTPLDVVKTRMQGLEASKYKNTAHCA 271

Human   271 LQILKKEGLKAFYKGTVPRLGRVCLDVAIVFVIYDEVVKLLNKVW 315
            ::|||.||..|||||||||||||||||||.|:|||..:.|.||||
  Fly   272 VEILKNEGPAAFYKGTVPRLGRVCLDVAITFMIYDSFMDLFNKVW 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC25A1	NP_001243463.1	PTZ00169	38..311	CDD:240302	185/272 (68%)
		Mito_carr	38..121	CDD:278578	56/82 (68%)
		Mito_carr	<148..220	CDD:278578	47/71 (66%)
		Mito_carr	223..313	CDD:278578	66/89 (74%)
sea	NP_001027175.1	PTZ00168	34..302	CDD:185494	181/267 (68%)
		Mito_carr	34..117	CDD:278578	55/82 (67%)
		Mito_carr	125..220	CDD:278578	61/94 (65%)
		Mito_carr	235..314	CDD:278578	60/78 (77%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	132	1.000	Domainoid score	I5132
eggNOG	1	0.900	-	-		E1_KOG0756
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	401	1.000	Inparanoid score	I1939
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58666
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002928
OrthoInspector	1	1.000	-	-		oto90200
orthoMCL	1	0.900	-	-		OOG6_104005
Panther	1	1.100	-	-	LDO	PTHR45788
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1828
SonicParanoid	1	1.000	-	-		X3276
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.860