Protein Alignment SLC25A1 and mce1

DIOPT Version :10

• Sequence 1: NP_001243463.1
• Gene: SLC25A1 / 6576
• HGNCID: 10979
• Length: 318
• Species: Homo sapiens
• Sequence 2: NP_594420.1
• Gene: mce1 / 2542456
• PomBaseID: SPAC19G12.05
• Length: 291
• Species: Schizosaccharomyces pombe
• Alignment Length: 301
• Identity: 116/301 - (38%)
• Similarity: 176/301 - (58%)
• Gaps: 23/301 - (7%)

Human    13 PKSGTGEGPERQRPGGSLRSGFPVPAGGLAGGIEICITFPTEYVKTQLQLDERSHPPRYRGIGDC 77
            |||....||.:.           :.|||:||.|||.||:|.|:.||:|||        ||.: :.
pombe     9 PKSSNKPGPVKS-----------IIAGGVAGAIEISITYPAEFAKTRLQL--------YRNV-EG 53

Human    78 VRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFEFLSNHMRDAQGRLDSTRGLLCGLGAGVAE 142
            .:..:...| |..|||.|:::.|:..||||||..|:.:...:.|..|.|...|.:|.||||||||
pombe    54 TKAKLPPFG-LEWYRGCSTVIVGNSLKAAVRFFAFDSIKKSLSDEHGHLTGPRTVLAGLGAGVAE 117

Human   143 AVVVVCPMETIKVKFIHDQTSPNPKYRGFFHGVREIVREQGLKGTYQGLTATVLKQGSNQAIRFF 207
            :|:|:.|.|:||...|.|:..|||:.:||....|.||.|.|::|.|:||.|||.:|.:|..:||.
pombe   118 SVLVLTPFESIKTAIIDDRKRPNPRLKGFLQASRIIVHENGIRGLYRGLAATVARQAANSGVRFT 182

Human   208 VMTSLRNWYRGD-NPNKPMNPLITGVFGAIAGAASVFGNTPLDVIKTRMQGLEAHK-YRNTWDCG 270
            ...|::...:.. .|::.::.:.|.:.|::||..:|:...|:|.:|:|||.|.|.| |:|:..|.
pombe   183 AYNSIKQSLQSRLPPDEKLSTVTTFLVGSVAGIITVYCTQPIDTVKSRMQSLSASKEYKNSIHCA 247

Human   271 LQILKKEGLKAFYKGTVPRLGRVCLDVAIVFVIYDEVVKLL 311
            .:||.::||..|:.|..|||.|:.|...|||.:|::|:::|
pombe   248 YKILTQDGLLRFWSGATPRLARLILSGGIVFTVYEKVMEIL 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC25A1	NP_001243463.1	Mito_carr	38..121	CDD:395101	33/82 (40%)
		Mito_carr	<148..220	CDD:395101	28/72 (39%)
		Mito_carr	223..313	CDD:395101	34/90 (38%)
mce1	NP_594420.1	Mito_carr	13..96	CDD:395101	35/103 (34%)
		Mito_carr	99..195	CDD:395101	42/95 (44%)
		Mito_carr	199..288	CDD:395101	33/88 (38%)