Protein Alignment BMPR1A and bmpr1aa

DIOPT Version :10

• Sequence 1: NP_001393488.1
• Gene: BMPR1A / 657
• HGNCID: 1076
• Length: 557
• Species: Homo sapiens
• Sequence 2: NP_571696.2
• Gene: bmpr1aa / 58145
• ZFINID: ZDB-GENE-000502-1
• Length: 527
• Species: Danio rerio
• Alignment Length: 555
• Identity: 405/555 - (72%)
• Similarity: 451/555 - (81%)
• Gaps: 33/555 - (5%)

Human     4 LYIYIRLLGAYLFI-ISRVQGQNLDSMLHGTGMKSDSDQKKSENGVTLAPEDTLPFLKCYCSGHC 67
            |:|.:.|.|..|.: :....|||.|.:|.|||:|.||  ::..:..|:||||...||.|:|||||
Zfish     5 LFITVVLTGVCLLLTLCSGAGQNPDHVLQGTGVKLDS--RRPGDDSTIAPEDAARFLSCHCSGHC 67

Human    68 PDDAINNTCITNGHCFAIIEEDDQGETTLASGCMKYEGSDFQCKDSPKAQLRRTIECCRTNLCNQ 132
            ||||.||||.|||.||||||||:.|:..|:|||||||||.||||||..||.|||||||:.:.|||
Zfish    68 PDDAKNNTCETNGQCFAIIEEDENGDVILSSGCMKYEGSHFQCKDSQFAQTRRTIECCQFDFCNQ 132

Human   133 YLQPTLPPVVIGPFFDGSIRWLVLLISMAVCIIAMIIFSSCFCYKGHLLLRVIHIRGQLESEGGV 197
            .|:|.|||....|   ....||..|||:.||..|:|      |                     |
Zfish   133 DLKPELPPRDSEP---PDPHWLAFLISVTVCFCALI------C---------------------V 167

Human   198 PVVLRHYCKSISSRRRYNRDLEQDEAFIPVGESLKDLIDQSQSSGSGSGLPLLVQRTIAKQIQMV 262
            .|:..:..|..:.|:||:|||||||||||.||||||||:|||:||||||||||||||||||||.|
Zfish   168 TVICYYRYKWQTERQRYHRDLEQDEAFIPAGESLKDLINQSQTSGSGSGLPLLVQRTIAKQIQTV 232

Human   263 RQVGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQTVLMRHENILGFIAADIKGTGSW 327
            |.:|||||||||:|:|||||||||||||.||||||||||||||||||||||||||||||.|||:.
Zfish   233 RMIGKGRYGEVWLGRWRGEKVAVKVFFTREEASWFRETEIYQTVLMRHENILGFIAADINGTGAS 297

Human   328 TQLYLITDYHENGSLYDFLKCATLDTRALLKLAYSAACGLCHLHTEIYGTQGKPAIAHRDLKSKN 392
            |||||||||||||||||:||..||||:|||:||:|||||||||||||||||||||||||||||||
Zfish   298 TQLYLITDYHENGSLYDYLKFTTLDTQALLRLAFSAACGLCHLHTEIYGTQGKPAIAHRDLKSKN 362

Human   393 ILIKKNGSCCIADLGLAVKFNSDTNEVDVPLNTRVGTKRYMAPEVLDESLNKNHFQPYIMADIYS 457
            |||||||:||||||||||||||||||||:||:||:||:||||||||||:|||||||.||||||||
Zfish   363 ILIKKNGTCCIADLGLAVKFNSDTNEVDLPLSTRMGTRRYMAPEVLDETLNKNHFQAYIMADIYS 427

Human   458 FGLIIWEMARRCITGGIVEEYQLPYYNMVPSDPSYEDMREVVCVKRLRPIVSNRWNSDECLRAVL 522
            :||:||||||||:|||||||||||||.|||||||||||.||||||.|||.|||||||||||||:|
Zfish   428 YGLVIWEMARRCVTGGIVEEYQLPYYEMVPSDPSYEDMLEVVCVKGLRPTVSNRWNSDECLRAML 492

Human   523 KLMSECWAHNPASRLTALRIKKTLAKMVESQDVKI 557
            ||||||||||||||||.||:||||||||||||:||
Zfish   493 KLMSECWAHNPASRLTILRVKKTLAKMVESQDIKI 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BMPR1A	NP_001393488.1	TFP_LU_ECD_BMPR1A	57..140	CDD:467132	59/82 (72%)
		TGF_beta_GS	230..257	CDD:462503	24/26 (92%)
		STKc_BMPR1a	263..549	CDD:271122	254/285 (89%)
bmpr1aa	NP_571696.2	TFP_LU_ECD_BMPR1A	57..140	CDD:467132	59/82 (72%)
		TGF_beta_GS	200..227	CDD:462503	24/26 (92%)
		STKc_BMPR1a	233..519	CDD:271122	254/285 (89%)