Protein Alignment SLC16A2 and CG10019

DIOPT Version :10

• Sequence 1: NP_006508.2
• Gene: SLC16A2 / 6567
• HGNCID: 10923
• Length: 539
• Species: Homo sapiens
• Sequence 2: NP_001368939.1
• Gene: CG10019 / 33600
• FlyBaseID: FBgn0031568
• Length: 1159
• Species: Drosophila melanogaster
• Alignment Length: 509
• Identity: 117/509 - (22%)
• Similarity: 215/509 - (42%)
• Gaps: 84/509 - (16%)

Human    53 PEPQPLPD--PAPLPEL-EFESERVHEPEP----TPTVETRGTARGFQPPEGGFGWVVVFAATWC 110
            |.|..:.|  .:..|.| :.|...:|...|    |....||  .|.:..|:||:||::      |
  Fly   392 PHPSHITDEEDSAFPGLADREFHLLHRNIPALRRTGVDTTR--IRQYFYPDGGWGWII------C 448

Human   111 NGSIF------GIHNSVGILYSMLLEEEKEKNRQVEFQAAWVGALAMGMIFFCSPIVSIFTDRLG 169
            ..|..      |:..|.|:|:...: :.......:|.    :|||:..:....:..|.....:..
  Fly   449 GVSFLVHILTTGLQLSYGLLWFYAV-QYLHNTSGIEL----LGALSWSVSMVATSFVVSLCRKRS 508

Human   170 CRITATAGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGCSFAFQPSLVILGHYFQRRLGLANGV 234
            .|:.:..|..|..:|:..:||.:......|:|||:||.|.:...:.|.|:||:||:||......|
  Fly   509 IRLLSIVGGLVMPLGILFTSFATEFGQVVFSYGIVFGVGVAMVREASTVMLGNYFKRRRQFVEMV 573

Human   235 VSAGSSIFSMSFPFLIR--------MLGDKIKLAQTFQVLSTFMFVLMLLSLTYRPLLPSSQDTP 291
            ..:|..:....|..:::        .||.:|..|.|  .||.||      .|.||   |:|...|
  Fly   574 AMSGEGVGIALFSVILKEGVGKAGWRLGLQIVAALT--ALSFFM------GLMYR---PASLYHP 627

Human   292 SKRGVRTL-HQR--------FLAQ----LRKYFNMRV--FRQRTYRIWAFGIAAAALGYFVPYVH 341
            .:|.::.| :||        .|:|    ..|||.:.:  .:..|.:|.....:.|:.|.:.|...
  Fly   628 QRRAIQHLKNQRKKMREKKPILSQDVESTPKYFFLDISSLKSVTVKILLMTSSVASFGIYTPMFL 692

Human   342 LMKYVEEEFSEIKETWVLLVCIGATSGLGRLVSG----------HISDSIPGLKKIYLQVLSFLL 396
            :.....|:.|:::|..:|...:|.:..||.:::|          |...:...:.:::|.:::..:
  Fly   693 MALNAAEQGSDVQELVLLQTFLGISMALGVVIAGALLRRCFVIRHFVINTKIVTQLFLSIVALAI 757

Human   397 LGLMSMMIPLCRDFGGLIVVCLFLGLCDGFFITIMAPIAFELVGPMQASQAIGYLLGMMALPMIA 461
            |.|..:|     .:.||.::....|:..|.|...:..:|.|.:.....|:|.|::.|:.::|::.
  Fly   758 LFLSFVM-----GYTGLCILSWLYGIGLGGFQYSLKILALERIKLKHFSKAWGFIRGVESVPVLI 817

Human   462 GPPIAGLLRNCFGDY-----HVAFYFAGVPPIIGAVILFFVPLMHQRMFKKEQR 510
            ..|:...|    .||     ...:|.......|..:|:||:....|:..:::|:
  Fly   818 SVPLTSFL----NDYSLKYGRAGYYICSAAAAISGIIIFFISEPQQQHQQQQQQ 867

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC16A2	NP_006508.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..92		12/45 (27%)
		MFS_MCT8_10	100..498	CDD:340978	100/441 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	508..539		1/3 (33%)
CG10019	NP_001368939.1	MFS_MCT_SLC16	444..840	CDD:340910	96/426 (23%)