Protein Alignment SLC16A2 and CG8051

DIOPT Version :10

• Sequence 1: NP_006508.2
• Gene: SLC16A2 / 6567
• HGNCID: 10923
• Length: 539
• Species: Homo sapiens
• Sequence 2: NP_573377.1
• Gene: CG8051 / 32925
• FlyBaseID: FBgn0031012
• Length: 616
• Species: Drosophila melanogaster
• Alignment Length: 591
• Identity: 114/591 - (19%)
• Similarity: 190/591 - (32%)
• Gaps: 209/591 - (35%)

Human    49 PEPQPEPQPLPDP--------APLPELEFESERVHEPEPTPTVETRGTA---RGFQPPEGGFGWV 102
            ||.|.| |.||..        || |...........|:..|..:.|..:   ..|..|:||:||:
  Fly    25 PEEQAE-QLLPKNGSAGQTKIAP-PTHTHSIAAASVPQKVPAKKKRDKSDLGEDFVAPDGGWGWL 87

Human   103 VVFAATWCNGSIFGIHNSVGILYSMLLEEEKEKNRQVEFQAAWVGALAMGMIFFCSPIVSIFTD- 166
            |..|:.......|.:....|||:         ::|..   ...:.:..:..|......||.||.
  Fly    88 VSVASGVNILVTFALAQQFGILF---------RDRMA---GLGISSSELTTIINTQIAVSAFTGL 140

Human   167 -------RLGCRITATAGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGCSFAFQPSLVILGHYF 224
                   |...|:.|..|:.:.|:||....|..:.::...::.||:|.|.......|.:.:..||
  Fly   141 LNGPLFRRYTYRVVALVGSVLTFLGLFWMVFADTFAVYIMSFSILYGFGRGLTVSASSLAVNTYF 205

Human   225 --QRRLGLA--NGVVSAGSSIFSMSFPFLIRMLGDKIKLAQTFQVLSTFMFV-----LMLLSLTY 280
              :||...|  .||...|..:......:::...|.:         .:|.:|.     .:..||.|
  Fly   206 KVKRRTATAFQFGVAGLGPIVCPYFATYMLYEFGVQ---------GTTLLFAGASLHTIACSLIY 261

Human   281 R-----------------------------------------PLLP------------------- 285
            :                                         |:||
  Fly   262 QPVKWHVVKRDRDAEALQQVQPLAEREDQDEDIIKNVVEPETPVLPRANDGWFGSRASLNSVGTR 326

Human   286 --------------------SSQDTPSKRGVRTL------------------------------- 299
                                ||:|:...|.:|::
  Fly   327 NRLNTWEKSDSNGHVELKRLSSKDSNPGRQLRSISVSHSIKEEEATGYNSDHEVQHTELTEKEKQ 391

Human   300 -------HQR-----FLAQLRKYFNMRVFRQRTYRIWAFGIAAAALGYFVPYVHLMKYVEEEFSE 352
                   .||     |..::..:|:|.:.|..||...|.||.            |:.:||..|:.
  Fly   392 ELEDEKERQRRKKLPFYMKVVIFFDMDLLRDITYVNLAVGIT------------LINFVEINFAI 444

Human   353 IKETWVLLVCIG----------ATSGLGRLVSGHISDSIPGLKKIYLQVLSFLLLGLMSMMI--- 404
            :  |..:|..:|          :|.|...||...:...|..  ||.|...:|.::|::.|.|
  Fly   445 L--TPFILSDLGFNKDQIALAMSTLGFFDLVVRFLIPLITA--KINLSNRTFFVVGILGMCIGRM 505

Human   405 --PLCRDFGGLIVVCLFLGLCDGFFITIMAPIAFELVGPMQASQAIGYLLGMMA--LPMIAGPPI 465
              .:..:|..::.:.|:||| :..|.|:...:......|::...|...|..:|:  ..||.| |:
  Fly   506 FLSMTSNFYVMMAIFLWLGL-NKAFRTVFWSLIIPSYVPLKRLPAAAGLQLLMSGTFSMIFG-PL 568

Human   466 AGLLRN 471
            .||:|:
  Fly   569 IGLIRD 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC16A2	NP_006508.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..92		13/53 (25%)
		MFS_MCT8_10	100..498	CDD:340978	97/529 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	508..539
CG8051	NP_573377.1	MFS_MCT_SLC16	85..599	CDD:340910	97/529 (18%)