Protein Alignment SLC16A2 and CG8028

DIOPT Version :10

• Sequence 1: NP_006508.2
• Gene: SLC16A2 / 6567
• HGNCID: 10923
• Length: 539
• Species: Homo sapiens
• Sequence 2: NP_001097031.2
• Gene: CG8028 / 32923
• FlyBaseID: FBgn0031010
• Length: 563
• Species: Drosophila melanogaster
• Alignment Length: 565
• Identity: 110/565 - (19%)
• Similarity: 184/565 - (32%)
• Gaps: 204/565 - (36%)

Human    93 QPPEGGFGWVVVFAATWCNGSIFGIHNSVGILYSMLLEEEKEKNRQVEFQAAWVGA--LAMGMI- 154
            :.|:||:|.:|.........|......|.|:::...|:.              :||  .||.:|
  Fly    32 EAPDGGWGILVCIGMALPFTSALAALPSFGLVFGEFLKS--------------IGAETSAMAIIT 82

Human   155 --FFCS-PIVSIFT----DRLGCRITATAGAAVAFIGLHTSSF-TSSLSL-------RYFTYGIL 204
              ||.| ....:|:    .|.|.|.....|..:.|:|.....| ||:|.|       :.|.:|::
  Fly    83 SAFFSSMSFAGLFSGSLFQRFGMRQVGVTGGILYFLGTGMQLFATSTLHLIMAFSVVQGFAFGLM 147

Human   205 F-GCGCSFAFQPSLVILGHYFQRR----LGLANGVVSAGSSIFSMSFPFLIRMLGDKIKLAQTFQ 264
            . .|..:|         .|||.:.    :..|..::..|    ||.:|.:::.|
  Fly   148 VPTCYTTF---------NHYFVKNRVMWMSFAQTLIGLG----SMLYPIVMQKL----------- 188

Human   265 VLSTFMFVLMLLSLT---------------------YRPLLPSSQ----------------DTPS 292
             :|.:.|...||.||                     ..|:.|..|                :||.
  Fly   189 -MSWYGFRGCLLILTGLNAHAVFGMLVMHPVEWHMRRVPIQPEEQEELKELSPTVVIRVQPETPL 252

Human   293 KR------------GVRTL-HQRFLAQLRKYFNMRVFRQRTYRIWAFGIA--------------- 329
            |.            |.|.| |..  .|:.|..:.|.....:...|:..:.
  Fly   253 KATREEPNFHTADPGARKLSHAE--EQMLKVLSSRASSITSLGNWSGPVVVSDASPQMMHSLQTS 315

Human   330 ------AAALGYFVPYVHLMK--YVEE-----EFSEIKETWVLLVCIGATSGLGRLVSGHISD-S 380
                  |.|.|...| .|..|  :|..     :.:.:|:...:.:.:|.|..|       .|| :
  Fly   316 RRPSTIAGASGAVAP-AHATKKSWVRTIVDFLDLTLLKKPIFVNIVLGITFAL-------YSDIT 372

Human   381 IPGLKKIYLQVLSF--------LLLGLMSMMIPLCRDFGGLIVVCL-----FLGLCDGFFITIMA 432
            ...::.:||..|.:        :.:|..:.:  ..|.|..:..||:     ::.|....| |:.|
  Fly   373 FFTMQPVYLFELGYSRPDTATIIAIGAAADL--ASRIFLAITAVCIQVPSRYIYLAGAVF-TVFA 434

Human   433 PIAF----ELVGPMQASQAIGYLLGMMALPM----------------------IAG------PPI 465
            ..||    :.||....:..||:|...:.:|:                      |.|      .||
  Fly   435 RFAFNGITQFVGMACITAVIGFLRTWLHVPLPLVFADYLPKERFATGYGLFMFIQGNAMFLIGPI 499

Human   466 AGLLRNCFGDYHVAFYFAGVPPIIGAVILFFVPLMHQRMFKKEQR 510
            .|.:|:...||...|:.     :.|.:||...|.:.:.:..|.:|
  Fly   500 VGFIRDKTRDYIFVFHI-----LNGFMILCAAPWVLEVLIVKFRR 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC16A2	NP_006508.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..92
		MFS_MCT8_10	100..498	CDD:340978	104/544 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	508..539		1/3 (33%)
CG8028	NP_001097031.2	MFS_MCT_SLC16	39..531	CDD:340910	105/548 (19%)