Protein Alignment SLC16A2 and CG14196

DIOPT Version :9

• Sequence 1: NP_006508.2
• Gene: SLC16A2 / 6567
• HGNCID: 10923
• Length: 539
• Species: Homo sapiens
• Sequence 2: NP_573367.1
• Gene: CG14196 / 32915
• FlyBaseID: FBgn0031002
• Length: 600
• Species: Drosophila melanogaster
• Alignment Length: 596
• Identity: 103/596 - (17%)
• Similarity: 180/596 - (30%)
• Gaps: 210/596 - (35%)

Human    92 FQPPEGGFGWVVVFAATWCNGSIFGIHNSVGILYSMLLEEEKEKNRQVEFQAAWVGALAMGMIFF 156
            |..|:.|:.|:|..||...|.||:......|.|:...|.:....:.|:.            .|..
  Fly    34 FVAPDAGWAWIVCVAAGVSNLSIYPCLQQFGFLFRERLSDLGMSSSQIT------------AIIN 86

Human   157 CSPIVSIFTD--------RLGCRITATAGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGCSFAF 213
            .:|.||..|.        |...|..|.||:.:....|..::|..:.......|.:|||.|...:.
  Fly    87 ANPAVSACTGLLNGPMFRRFTFRQVAMAGSLLISGSLILTAFCETFLSYMVAYALLFGFGMGISV 151

Human   214 QPSLVILGHYFQRRLGLANG----VVSAGSSIFSMSFPFLIRMLGDKIKLAQTFQVLSTFMFVLM 274
            ..|.:.:..|||::...|.|    :...|.........||:.:.|.: .....|..:|...||..
  Fly   152 SASSLAINTYFQKKRRRAAGFSWTITGLGPIFLPHLVTFLLTIYGVQ-GTTLLFAAISLHSFVCA 215

Human   275 LLSLTYR---------------------------------------------------------- 281
            |:....|
  Fly   216 LIYQPVRYHVKPPVEQLADQEQQAEALCAHCSWQQKREPGGIFSSQYLCQDDDAQRPGYEICEPG 280

Human   282 -PLLPSSQD---------TPSKRGVRT-------------------------------------- 298
             |:|..:.|         |..:...||
  Fly   281 TPMLSRANDGWYGSRLSLTSGRLRFRTISSSKDLEQTQRLHCPISEEQNHESDEFLRPNNFRRER 345

Human   299 ----------------------------------------LH---QRFLAQLRKYFNMRVFRQRT 320
                                                    ||   ..|||::..:|::.:.|..|
  Fly   346 VESNLEAKLCCQCSAKREEHNNNRKEKEAEAEEAGMESAPLHDPQMSFLAKVVTFFDLDLLRDFT 410

Human   321 YRIWAFGIAAAALG-----YFVPYVHLMKYVEEEFSEIKETWVLLVCIGATSGLG---RLVSGHI 377
            :.....|:.....|     ...|::    .|:..|    :|..:.:.:...:||.   |.:...:
  Fly   411 FVNLVAGLTIINFGELNFSILTPFI----LVDFGF----DTPQITLAMSLLAGLDITMRFMVPFL 467

Human   378 SDSIPGLKKIYLQVLSFLLLGLMSM-----MIPLCRDFGGLIVVCLF--LGLCDGFFITIMAPIA 435
            ::.||...::      |.|:|::.:     ::...|.:.  :::|.|  :|||.| ..||..|:.
  Fly   468 TEKIPWDNRV------FFLIGVVGIALGRTVVACTRSYS--LILCSFVWIGLCKG-VRTIFWPLI 523

Human   436 FELVGPM-QASQAIGYLLGMMALPMIAGPPIAGLLRNCFGDYHVAFYFAGVPPIIGAVILFFVPL 499
            .....|: :...|.|..|.:..|..:.|.|..||:|:.: ||.|..:...:...:.|.......|
  Fly   524 IPGYVPLNRLPGASGLQLLISGLFTLIGGPFVGLVRDRY-DYSVTLHCLNMMSFVAATSWSLEAL 587

Human   500 MHQRMFKKEQR 510
            :  |..:::||
  Fly   588 I--RRHRRKQR 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC16A2	NP_006508.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..92		103/596 (17%)
		2A0113	86..513	CDD:273325	103/596 (17%)
		MFS	101..498	CDD:119392	96/573 (17%)
		DUF1564	<286..>334	CDD:284922	13/137 (9%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	508..539		2/3 (67%)
CG14196	NP_573367.1	MFS	71..>221	CDD:119392	34/162 (21%)
		MFS	<410..579	CDD:119392	38/186 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145510
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750