Protein Alignment SLC16A1 and kar

DIOPT Version :10

• Sequence 1: NP_003042.3
• Gene: SLC16A1 / 6566
• HGNCID: 10922
• Length: 500
• Species: Homo sapiens
• Sequence 2: NP_001189213.1
• Gene: kar / 45883
• FlyBaseID: FBgn0001296
• Length: 612
• Species: Drosophila melanogaster
• Alignment Length: 489
• Identity: 113/489 - (23%)
• Similarity: 199/489 - (40%)
• Gaps: 84/489 - (17%)

Human    10 GYTPPDGG-WGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHA-------------TTSEVSW 60
            |..||||| ..|.|::.||:..|..:.|   |..:     |:.|:             .:|:.:.
  Fly    70 GKEPPDGGARAWLVMVSAFLCNGIIFGF---INTY-----GVIHSLLTDRLTKLGDPEASSKAAL 126

Human    61 ISSIMLAVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFC-NTVQQLYVCIGVIGGLGL 124
            |.::.:...:....::..|.:|.|.|:....||.||..||:.:||| ..:..||...|::.|||.
  Fly   127 IGALAIGTTFLFSTMAGCLTDKIGLRLTTFAGGVLSAGGLLLSSFCTENIGALYFTYGIMFGLGA 191

Human   125 AFNLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCC 189
            |....|.|.::|.||.:.....:|...|||.||...|.|......|.:|..|:..|:..:.....
  Fly   192 ALAYTPTLAILGHYFKRYLGKVSGFVTAGSSVFTVILPPCLDKLLGSYGLEGTLRIMSLVSAFII 256

Human   190 VAGALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQEKRSVFQTINQFLD 254
            :...:.:|:.|.|....|        |.|:|.:...|                ||:       ::
  Fly   257 LCSFVYKPLHPPPEPPKK--------KPGRSRINLFL----------------RSI-------IN 290

Human   255 LTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAFLLSILAFVDMVARPSMGLV 319
            :.::..:.|:::.....:..||.|.|.|.:..:.|:. :..|.....:..:.....:.|...|::
  Fly   291 VEIWKRKRFVIWALCVPLALFGYFVPYVHMMQFVKTT-FPGEDVNLPVMCIGITSGIGRLIFGVI 354

Human   320 ANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTY---VGFCVYAGFFGFAFGWLSSVLFETLMDL 381
            |:...:..  .|....|:|:.|:..:|.||:.:|   |.|.:..|.|.   |...|:|.....::
  Fly   355 ADMPGVNR--MYLQQLSLVSIGLVTLLLPLTNSYVILVSFTLVMGLFD---GCFISLLGPIAYEI 414

Human   382 VGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVVLIISGIYLFIGMGINYR 446
            .||...:.|:|.:..:...|:.:|||:.|.:.|....|.       :.||::|:...:|..:.:.
  Fly   415 CGPSGATQAIGFLLGLSSIPLTVGPPVAGMIFDSTNSYT-------LPLILAGLPPLLGSSLLFL 472

Human   447 LLAKEQKANEQKKESKEEETSIDVAGKPNEVTKA 480
            :           |..||||..:..   |..|..|
  Fly   473 I-----------KCVKEEENGVSA---PRAVVLA 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC16A1	NP_003042.3	2A0113	1..455	CDD:273325	105/462 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	454..500		8/27 (30%)
kar	NP_001189213.1	MFS_MCT8_10	80..474	CDD:340978	99/456 (22%)