Protein Alignment SLC16A1 and CG13907

DIOPT Version :9

• Sequence 1: NP_001159968.1
• Gene: SLC16A1 / 6566
• HGNCID: 10922
• Length: 500
• Species: Homo sapiens
• Sequence 2: NP_001286894.1
• Gene: CG13907 / 38104
• FlyBaseID: FBgn0035173
• Length: 816
• Species: Drosophila melanogaster
• Alignment Length: 771
• Identity: 164/771 - (21%)
• Similarity: 243/771 - (31%)
• Gaps: 310/771 - (40%)

Human     1 MPPAVGGPVGYTPPDGGWGWAVVIGAF----ISIGFSYAFPKSITVFFKEIEGIFHATTSEVSWI 61
            :||         |||||:||.:...:|    |..|.:|.|    .:|.:|....||.....|:|:
  Fly    68 LPP---------PPDGGYGWVICFASFMCNMIVDGIAYTF----GIFLEEFVAYFHEGKGTVAWV 119

Human    62 SSIMLAVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAF 126
            .|::..|....|||.|.|.||||.|.|.|.|..::....:.::|...|..|....|.:||.|...
  Fly   120 GSLLSGVYLSAGPIVSALANKYGCRAVCIAGSIIACIAFVLSTFSTNVSMLMATYGFMGGFGFGM 184

Human   127 NLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCCVA 191
            ...||:..:|.||..:|.||.|:|:.||.......|||.......:||:.:.||..||:|||.:.
  Fly   185 IYLPAVVAVGYYFETKRSLATGIAVCGSGFGTFAFAPLATYLLEEYGWKNALLIFAGLILNCAIF 249

Human   192 GALMRPIG-PKPTK---------------------AG------------KDKSKASL-------- 214
            ||:|||:. ||..|                     ||            :.|.|..|
  Fly   250 GAMMRPLTYPKKKKQKPLMQRMYEEKQLQLERGSFAGSHFMVQLPDGTIERKLKMPLNADPGVHS 314

Human   215 --------EKAGKSGVKK-------------DLH-----------DANTDL--------IGRHP- 238
                    ::||..|:..             |:|           |:|..|        :||.|
  Fly   315 SLNLELLAQQAGGGGLHPVSTLPTITESKVVDVHRQNGAQSPPNGDSNGQLSARSAAGAVGRRPH 379

Human   239 ----------------------------------------------------------------- 238
                                                                             
  Fly   380 RNSESENSPYHSQDAMTRNASQPAFLAGDHQSLPKNGSVPAFNTRVRKTSASERFQPSLAAIRAT 444

Human   239 ----------------------------------------------------------------- 238
                                                                             
  Fly   445 SRGDLEAGAGGDFASSKLSLSQRQGGSQTGSSGRMVRPMSRKDIFYSGSVTNLPQYQSQKSLANY 509

Human   239 --------KQEKR------------------------------SVFQTINQFLDLTLFTHRGFLL 265
                    |.||.                              ||...:|..||::|.....|:|
  Fly   510 RNSVLSLTKYEKSMQSVAKLDPLAEAEKHREEYDLCPCLGIPDSVKSVVNTMLDVSLLKDPVFML 574

Human   266 YLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAFLLSILAFVDMVARPSMGLVANTKPIRPRIQ 330
            ....|:....||:.|.|:|....|........:|.||||:...:.|.|...|.||:.    |::.
  Fly   575 IGVSNIFGMAGLYVPFVYLVDAAKEHDIPKNDAAMLLSIIGITNTVGRVFCGWVADL----PQVN 635

Human   331 YFFAASVVANGVCHM-------LAPLSTTYVGFCVYAGFFGFAFGWLSSVLFETLMDLVGPQRFS 388
                 |::.|..|.:       |.||..:|..:...:.|||.|.....|:....|:||:|..:.:
  Fly   636 -----SLLLNNCCLLVSTIAVTLTPLCYSYAAYITMSIFFGLAISGYISLTSIILVDLLGLDKLT 695

Human   389 SAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVVLIISGIYLFIGMGINYRLLAKEQK 453
            :|.||:.:......|:|.||.|.:.||...|...::..|.:..||.|..|:...:
  Fly   696 NAFGLLILFRGFAALIGTPLAGAIYDMTHTYDLPFYMAGALFGISTITSFLAPCL---------- 750

Human   454 ANEQKKESKEEETSIDVAG-KPNEVTKAAESPDQKD-----------TDGGPKEEE 497
                |:.|..|||.:.|.. .|.:..:..::.|.:|           |...|::||
  Fly   751 ----KRCSPSEETPVHVETLTPIDEEQGEDAEDDEDQPITIVPKIIKTLASPQQEE 802

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC16A1	NP_001159968.1	2A0113	1..455	CDD:273325	151/715 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	454..500		13/56 (23%)
CG13907	NP_001286894.1	MFS	78..>258	CDD:119392	63/183 (34%)
		MFS	<570..748	CDD:119392	52/186 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145548
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D916876at2759
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	1	1.000	-	-		mtm9818
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.850