Protein Alignment SLC16A1 and CG8389

DIOPT Version :10

• Sequence 1: NP_003042.3
• Gene: SLC16A1 / 6566
• HGNCID: 10922
• Length: 500
• Species: Homo sapiens
• Sequence 2: NP_611076.2
• Gene: CG8389 / 36764
• FlyBaseID: FBgn0034063
• Length: 471
• Species: Drosophila melanogaster
• Alignment Length: 498
• Identity: 119/498 - (23%)
• Similarity: 204/498 - (40%)
• Gaps: 71/498 - (14%)

Human    14 PDGGWGWAVVIGAFISIGFSYAFPKSI--TVFFKEIEGIFHATTSEVSWISSIMLAVMYGG---G 73
            ||||:|| :|:.|...|..:.....|:  .:|..|::.:...|.:.....:...||:.:.|   |
  Fly    10 PDGGYGW-IVVAAVALINMTNQSILSVFGQLFVGELQKMQEDTFTAALITNLNSLALNFSGLFIG 73

Human    74 PISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIG---VIG-GLGLAFNLNPALTM 134
            |    .:..:..|.|...|..|...||...:|.:  :..:..:|   .:| ||||   ::|:..|
  Fly    74 P----AIKSFKPRNVAATGCILVALGLALCAFAS--ESWHFILGYSFFVGFGLGL---ISPSTFM 129

Human   135 -IGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCCVAGALMRPI 198
             |..||..:|..|.|:::||:.:....:..|.:......|:|.:.|.:..|.|......|.::|:
  Fly   130 AINSYFTTKRGRAVGVSLAGAGLGQVLIPHLVRYLLDNHGFRYAVLSMSSLSLFGLFGAAFLKPL 194

Human   199 GPKPTKAGKDK-----SKASLEKAGKSGVKKDLHDANTDLIGRHPKQEK---RSVFQTINQFLDL 255
            .| |.|....|     ::|..||.  |.::..:...|...|.|.|....   ..:.|.:.|.:||
  Fly   195 NP-PAKHNNRKHIRLLTEADGEKT--SPLQVVIVPTNQSKIERSPPNVDTLCSRMGQRLVQAMDL 256

Human   256 TLFTHRGFLLYLSGNVIMFFG-LFAPLVFLSSYGKSQHYSSEKSAFLLSILAFVDMVARPSMGLV 319
            .|.....|...:.|..:::.. :...::|....|::...:|:..||.:|::|..|:|.|..:.:|
  Fly   257 ELLKDLVFWSIIVGMALVYTATINFTMIFPGFLGQTAQLNSQMVAFCMSLVAGADIVFRLLLPIV 321

Human   320 ANTKPIRPRIQY-------FFAASVVANGVCHMLAPLSTTYVGFCVYAGFFGFAFGWLSSVLF-- 375
            .:...|..|:.:       |.|..|:|.   :...|:..|   ..|..|....|....:::..
  Fly   322 TDHLRIPYRVVFLIGIVGLFVARCVLAE---NQTLPVIIT---MSVLTGMMKSATVINNNLTISA 380

Human   376 ----ETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVVLIISGIY 436
                |.|...:|....|..|.::|:.:         |||.:.|....|....:|.||:|::  :.
  Fly   381 HCRSEKLAGGLGLSMMSKGVIVITVGQ---------LLGWVRDYADSYLICLYAQGVILLV--VV 434

Human   437 LFIGMGINYRLLAKEQKANEQKKESKEEETSIDVAGKPNEVTK 479
            |.....|.||  .:.|:....|   ..|..|||.|    ||.|
  Fly   435 LVWTPEILYR--HRRQRCATNK---SMETQSIDAA----EVAK 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC16A1	NP_003042.3	2A0113	1..455	CDD:273325	110/472 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	454..500		9/26 (35%)
CG8389	NP_611076.2	MFS_MCT_SLC16	15..440	CDD:340910	102/454 (22%)