Protein Alignment SLC13A1 and CG7309

DIOPT Version :10

• Sequence 1: XP_011514817.1
• Gene: SLC13A1 / 6561
• HGNCID: 10916
• Length: 651
• Species: Homo sapiens
• Sequence 2: NP_609468.4
• Gene: CG7309 / 34509
• FlyBaseID: FBgn0032314
• Length: 528
• Species: Drosophila melanogaster
• Alignment Length: 655
• Identity: 131/655 - (20%)
• Similarity: 237/655 - (36%)
• Gaps: 198/655 - (30%)

Human    12 RFLFVVF----TVLVLLPL---PIVLHTKEAECAYTLFVVATF--WLTEALPLSVTALLPSLMLP 67
            |.||..:    .:|:.:|:   ||::.|....|.:....:..:  ::...:.....|.:..:.:|
  Fly    20 RRLFCKYHYKGVLLLFIPILLAPILIGTPVLICRFIYLTLCLYLIYILNLMARGAAAFIYMVFIP 84

Human    68 MFGIMPSKKVASAYFKDFHLLLIGVICLATSIEKWNLHKRIALKMVMMVGVNPAWLTLGFMSSTA 132
            :.||..||:::.:|:.|....:...|.:...::...|..|:|..::.:||.:..:|.:....:.|
  Fly    85 VAGIASSKEISVSYYTDLIFFVYSAIFMGIMMDSSKLSDRLAFIVISLVGGSLKFLQIFLTIAAA 149

Human   133 FLSMWLSNTSTAAMVMPIAEAVVQQIINAEAEVEATQMTYFNGSTNHGLEIDESVNGHEINERKE 197
            .:|:.::.|.:||..|.:::||:              :.|.||..   ::::.....:||..:..
  Fly   150 IVSILVNPTISAAFWMKVSQAVM--------------VEYDNGGL---IKLNSEEKPYEIGSKPY 197

Human   198 KTKPVPGYNNDTGKISSKVELEKEEEESNQQRVFTGSWVRKRMKLLLAYTLESHLLNKTLTFGLV 262
            .|:||.|                                   :.|...|...   |..:|:
  Fly   198 PTRPVIG-----------------------------------IYLTCCYAAS---LAASLS---- 220

Human   263 IPQVKPFQDVPLSKNSGMRTKYRTKKGHVTRKLTCLCIAYSSTIGGLTTITGTSTNLIFAEYFNT 327
             |.|.|         :|:                     .|...||..|:
  Fly   221 -PIVNP---------NGV---------------------ISDGFGGSLTV--------------- 239

Human   328 RYPDCRCLNFGSWFTFSFPAALIILLLSWIWLQWLFLGF-------NFKEM--FKCGKTKTVQQK 383
                   |..|  ...:.| ||:.|::...|||.||||.       :..||  .|.|..:|..::
  Fly   240 -------LEIG--MLMAGP-ALMGLVVMIFWLQVLFLGLLGGSVKRDLAEMAGAKAGFKQTASER 294

Human   384 ACAEVIKQEYQKLGPIRYQEIVTLVLFIIMALLWFSRDPGFVPGWSALFSEYPGFATDSTVALLI 448
            .         |.|||.....|:.|.|.::|.||..:|.|....||.::  .|...:..|...:.:
  Fly   295 K---------QALGPWGIYPILALSLILLMFLLVATRKPRIFTGWDSI--NYKAESGLSVAGIGM 348

Human   449 GLLFFLIPAKTL----------TKTTPTGEIVAFDYSPLITWKEFQSFMPWDIAILVGGGFALAD 503
            .:|||.|||..:          .|..|.        :.|:.||...:..||....::|..|:.:.
  Fly   349 SILFFAIPANYIFCRYYVCRQPEKEGPA--------NSLLGWKAVNNNTPWAEIFMLGAAFSFSY 405

Human   504 GCEESGLSKWIGNKLSP-----------LGSLPAWLIILISSLMVTSLTEVASNPATITLFLPIL 557
            .....||:.::.:.::.           .|:|...|...:|.  .|::.::|. |..:|......
  Fly   406 SSAVCGLNTYLADSMNSDNKGFNMKSFICGALLGTLWTTLSP--ATTVAKLAL-PTMVTAGNSFS 467

Human   558 SPLAEAIHVNPLYILIPSTLCTSFAFLLPVANPPNAIVFSYGHLKVIDMVKAGLGVNIVGVAVVM 622
            .|.|.|:|..               |||||::|.|.||..:|:::....:   ||    |..:.:
  Fly   468 LPFATALHNQ---------------FLLPVSSPANTIVAGWGNVRPFQFL---LG----GSILTL 510

Human   623 LGICT 627
            ...||
  Fly   511 FMFCT 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC13A1	XP_011514817.1	CitMHS	<7..171	CDD:460985	32/167 (19%)
		CitT	90..628	CDD:440239	114/568 (20%)
CG7309	NP_609468.4	CitT	108..523	CDD:440239	114/567 (20%)