Protein Alignment BMP7 and mav

DIOPT Version :10

• Sequence 1: NP_001710.1
• Gene: BMP7 / 655
• HGNCID: 1074
• Length: 431
• Species: Homo sapiens
• Sequence 2: NP_524626.1
• Gene: mav / 43804
• FlyBaseID: FBgn0039914
• Length: 701
• Species: Drosophila melanogaster
• Alignment Length: 278
• Identity: 63/278 - (22%)
• Similarity: 120/278 - (43%)
• Gaps: 54/278 - (19%)

Human   187 NETFRISVYQVLQEHLGRESDLFLLDSRTLWASEEG-------WLVFDITATSNHWVVNPRHNLG 244
            ::...:.|||:|..:..|:     :.||.:.....|       |:.||:|.....|:.....|||
  Fly   443 SQQLTLKVYQLLSANRRRK-----ITSRKIEFGNVGFQETRTQWIEFDVTKAVRSWLNKSHENLG 502

Human   245 LQLSVETLDGQSINPKL-------------------------AGLIGRHGPQNKQPFMVAFFKAT 284
            :::..:..  :||..::                         ..:|| ||..|.|....|
  Fly   503 IEIQCDKC--KSIGARILSDFSPSTPPRSTASSDEHLNLMPVLNIIG-HGTLNSQQHGDA----- 559

Human   285 EVHFRSIRSTGSKQRSQNRSKTPKNQEALRMANVAENSSSDQRQACKKHELYVSFRDLGWQDWII 349
            ::|...:.:..|.|...:||    |.::....:...|:.....|.|.:::|.|:|:.:...::|:
  Fly   560 DIHQIMLTNNRSDQYVHHRS----NHDSTWRKDKWTNNCYKLHQRCCRNQLDVAFKSIKGFEFIL 620

Human   350 APEGYAAYYCEGECAFPLNSYMNATNHAIVQTLVHFINPETVPKPCCAPTQLNAISVLYFDD--S 412
            .|:.:.|.||.|.|....|.   |.:||::|:|:...:.:..|:|||.|::|..:.:|:.|:  |
  Fly   621 QPKVFDAGYCHGRCPPRHNP---AHHHALLQSLIWQEDHKRAPRPCCTPSKLEMLEILHVDENHS 682

Human   413 SNVILKKYRNMVVRACGC 430
            ..:.:..:.:|.|..|.|
  Fly   683 DKLKISTWSDMQVVECAC 700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BMP7	NP_001710.1	TGFb_propeptide	35..280	CDD:459906	24/124 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	291..311		5/19 (26%)
		TGF_beta_BMP7	325..431	CDD:381667	31/108 (29%)
mav	NP_524626.1	TGFb_propeptide	<438..518	CDD:480997	18/81 (22%)
		TGF_beta_maverick	598..700	CDD:381633	30/104 (29%)