Protein Alignment BMP7 and daw

DIOPT Version :10

• Sequence 1: NP_001710.1
• Gene: BMP7 / 655
• HGNCID: 1074
• Length: 431
• Species: Homo sapiens
• Sequence 2: NP_523461.1
• Gene: daw / 33474
• FlyBaseID: FBgn0031461
• Length: 586
• Species: Drosophila melanogaster
• Alignment Length: 289
• Identity: 71/289 - (24%)
• Similarity: 125/289 - (43%)
• Gaps: 69/289 - (23%)

Human   165 EGEAVTAAEFRIYKDYIRERFD---------NETFRISVYQVLQEHLGRESDLFLLDSRTLWAS- 219
            ||..|:.|...::|:. :.|.|         .:|..:|..:|.|:.          ||:.|.|:
  Fly   343 EGFDVSTAVLWLFKNK-QNRTDTASVNSTSAQQTIVVSEVEVDQQK----------DSKYLSAAK 396

Human   220 ---------EEGWLVFDITATSNHWVVNPRHNLG--LQLSVETLDGQSINPKLAGLIGRHGPQNK 273
                     ::.|:..||.....||:..  |.|.  :|::....|...:...::      ..::.
  Fly   397 TIAIQSVNVQDEWMKIDIEWPIKHWISG--HELSHLIQITCGGCDVSDMEEIIS------VDKDY 453

Human   274 QPFMVAFFKATEVHFRSIRSTGSKQRSQNRSKTPKNQEALRMANVAENSSSDQRQACKKHELYVS 338
            :||:|.                   ..|||.:..:.:.::       |.||...:.|::| ||:|
  Fly   454 RPFIVI-------------------DMQNRRRKSRQKRSI-------NCSSGMTECCREH-LYIS 491

Human   339 FRDLGWQDWIIAPEGYAAYYCEGECAFPLNSYMNATNHAIVQTLVHF--INPETVPKPCCAPTQL 401
            |||:||.:||:.||||.||:|.|.|:...:....|::|:.:..::..  .|......|||...|.
  Fly   492 FRDIGWSNWILKPEGYNAYFCRGSCSSVASVTQAASHHSSIMKILSTSGANKSLELVPCCTAKQY 556

Human   402 NAISVLYFDDSSNVILKKYRNMVVRACGC 430
            :::.::..|.|:...:|...||||.:|||
  Fly   557 SSLQLVVMDSSNTATVKTLPNMVVESCGC 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BMP7	NP_001710.1	TGFb_propeptide	35..280	CDD:459906	27/135 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	291..311		3/19 (16%)
		TGF_beta_BMP7	325..431	CDD:381667	38/108 (35%)
daw	NP_523461.1	TGF_beta_INHB	483..585	CDD:381630	36/102 (35%)