Protein Alignment SLC7A1 and slif

DIOPT Version :10

• Sequence 1: NP_003036.1
• Gene: SLC7A1 / 6541
• HGNCID: 11057
• Length: 629
• Species: Homo sapiens
• Sequence 2: NP_649428.1
• Gene: slif / 40510
• FlyBaseID: FBgn0037203
• Length: 604
• Species: Drosophila melanogaster
• Alignment Length: 630
• Identity: 282/630 - (44%)
• Similarity: 388/630 - (61%)
• Gaps: 80/630 - (12%)

Human     6 LLNIGQQMLRRKVVDCSREETRLSRCLNTFDLVALGVGSTLGAGVYVLAGAVARENAGPAIVISF 70
            :.|:.:.:.|||..|.:..|::|:|.||.|||.|||||||||.|||||||.||...||||:.|||
  Fly     1 MTNLWKALTRRKTEDVNEGESQLARVLNLFDLTALGVGSTLGLGVYVLAGQVAFNIAGPAVTISF 65

Human    71 LIAALASVLAGLCYGEFGARVPKTGSAYLYSYVTVGELWAFITGWNLILSYIIGTSSVARAWSAT 135
            ||||:||..||:||.||.|||||.||||:|||||:||..||..||||||.|:|||:||||..|..
  Fly    66 LIAAIASAFAGICYAEFAARVPKAGSAYVYSYVTIGEFVAFTIGWNLILEYVIGTASVARGLSGY 130

Human   136 FDELIGRPIGEFSRTHMTLNAPGVLAENPDIFAVIIILILTGLLTLGVKESAMVNKIFTCINVLV 200
            ||.||...:.:.....|.::. ..|.:.||..:..::|:|..:|..|.|||:.:|.|||.:|::.
  Fly   131 FDSLINNNMSKALNESMHIDV-DFLGDYPDFLSFGMVLLLAAILAFGAKESSFLNNIFTTVNLVT 194

Human   201 LGFIMVSGFVKGSVKNWQLTEEDFGNTSGRLCLNNDTKEGKPGVGGFMPFGFSGVLSGAATCFYA 265
            :..::|:|.:..:|.||::.::             |..||. |.|||||||.:||::|||.|||.
  Fly   195 IAIVLVAGAMNANVDNWRIPKK-------------DVPEGF-GTGGFMPFGIAGVMAGAAKCFYG 245

Human   266 FVGFDCIATTGEEVKNPQKAIPVGIVASLLICFIAYFGVSAALTLMMPYFCLDNNSPLPDAFKHV 330
            |||||||||||||..||::.||:.||.||:|.|::|||||..||:|:||:..|.::|.|.||..|
  Fly   246 FVGFDCIATTGEEAINPKRNIPLSIVVSLIIIFLSYFGVSTVLTMMLPYYKQDKDAPFPHAFDSV 310

Human   331 GWEGAKYAVAVGSLCALSASLLGSMFPMPRVIYAMAEDGLLFKFLANVNDRTKTPIIATLASGAV 395
            .|...|:.|.:|::.||..||||:|||:||::|||.:||:|||.|:.||..||||::||:.||..
  Fly   311 EWYTIKWIVTIGAVFALCTSLLGAMFPLPRILYAMGKDGILFKRLSTVNSYTKTPLLATIVSGIF 375

Human   396 AAVMAFLFDLKDLVDLMSIGTLLAYSLVAACVLVLRYQPEQPNLVYQMASTSDELDPADQNELAS 460
            |::||.||:|..|||:|||||||||::||.||||||||.|
  Fly   376 ASIMAMLFNLDQLVDMMSIGTLLAYTIVAICVLVLRYQDE------------------------- 415

Human   461 TNDSQLGFLPEAEMFSLKTILSPKNM----------EPSKISGLIVNISTSLIAVLIITFCIVTV 515
                        ||..|.::.:|...          ||:.::..|..:...:.|:..:.:|
  Fly   416 ------------EMTKLVSVKAPNVFRQFFNGNSFREPNSMTSSITKVGIVVFAIFCLVWC---- 464

Human   516 LGREALTK-------GALWAVFLLAGSALLCAVVTGVIWRQPESKTKLSFKVPFLPVLPILSIFV 573
                :|.|       |.:.|:.|:....:|..||.|:   ||.|..:|:||||.:|.:|.||:|.
  Fly   465 ----SLQKVFDLDSTGGIVALSLVGAVLILICVVIGM---QPVSTIELTFKVPLVPFVPCLSVFA 522

Human   574 NVYLMMQLDQGTWVRFAVWMLIGFIIYFGYGLWHSEEASLDADQA 618
            |:|||.|||..||:||.:|::||::|||.||:.:|.:.|.....|
  Fly   523 NLYLMFQLDLNTWIRFLIWIVIGYVIYFCYGMRNSTQISRSRSHA 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC7A1	NP_003036.1	2A0303	4..610	CDD:273330	280/620 (45%)
slif	NP_649428.1	2A0303	8..557	CDD:273330	278/611 (45%)