Protein Alignment SLC7A1 and CG13248

DIOPT Version :10

• Sequence 1: NP_003036.1
• Gene: SLC7A1 / 6541
• HGNCID: 11057
• Length: 629
• Species: Homo sapiens
• Sequence 2: NP_649219.1
• Gene: CG13248 / 40254
• FlyBaseID: FBgn0036984
• Length: 669
• Species: Drosophila melanogaster
• Alignment Length: 628
• Identity: 253/628 - (40%)
• Similarity: 369/628 - (58%)
• Gaps: 52/628 - (8%)

Human     5 VLLNIGQQMLRRKVVDCSREETRLSRCLNTFDLVALGVGSTLGAGVYVLAGAVARENAGPAIVIS 69
            :|..|..:|.|.|.|.....||.|:|||||||:..||:|..:|||:|||.|.||:|.|||.|::|
  Fly    12 ILSGICTKMNRTKSVPTDVMETPLNRCLNTFDIALLGIGHMVGAGIYVLTGTVAKEMAGPGIILS 76

Human    70 FLIAALASVLAGLCYGEFGARVPKTGSAYLYSYVTVGELWAFITGWNLILSYIIGTSSVARAWSA 134
            |::|...|:||.|||.|||.||||.||||:|:|:::||.|||:.|||::|.:::|.:|||||||.
  Fly    77 FILAGFISMLAALCYAEFGTRVPKAGSAYVYTYISMGEFWAFVIGWNILLEHMLGAASVARAWSG 141

Human   135 TFDELIGRPIGEFSRTHMT--LNAPGVLAENPDIFAVIIILILTGLLTLGVKESAMVNKIFTCIN 197
            ..|.::|..||. :...:|  ::.|| ||:.||:.|.::.::....|..|||.:|:.|.:.|.:|
  Fly   142 YVDSMLGGWIGN-TTLELTGGIHEPG-LAQYPDVLAFLVCIVYAAALAGGVKATAVFNSLLTLVN 204

Human   198 VLVLGFIMVSGFVKGSVKNWQLTEEDFGNTSGRLCLNNDTKEGKPGVGGFMPFGFSGVLSGAATC 262
            :.|:..::..||.....|||...|                       |||:|:|..||::|||||
  Fly   205 IAVMVLVISVGFWYADGKNWSEAE-----------------------GGFLPYGVGGVIAGAATC 246

Human   263 FYAFVGFDCIATTGEEVKNPQKAIPVGIVASLLICFIAYFGVSAALTLMMPYFCLDNNSPLPDAF 327
            ||||||||.|||:|||.|||..:|||..|.||.:..:.|..||||||||:|...::..:.||:||
  Fly   247 FYAFVGFDSIATSGEEAKNPSVSIPVATVISLFVVTVGYILVSAALTLMIPISEINPAASLPEAF 311

Human   328 KHVGWEGAKYAVAVGSLCALSASLLGSMFPMPRVIYAMAEDGLLFKFLANVNDRTKTPIIATLAS 392
            ..:....|||.:::|:||.::.:||||:|.:||.:||||.|||||.....:|..|:.|::..:.|
  Fly   312 GQLNLSWAKYLISIGALCGMTTTLLGSLFALPRCMYAMASDGLLFSCFGKINPTTQVPLLNLVVS 376

Human   393 GAVAAVMAFLFDLKDLVDLMSIGTLLAYSLVAACVLVLRYQPEQ----PNLVYQMASTSDELDPA 453
            |.::|.:|.:|||..||:.|||||||||::|:|.|::|||:|.:    ...|..:|.:.|: |..
  Fly   377 GVMSACLALVFDLAKLVEFMSIGTLLAYTIVSASVIILRYRPMERIHTTIRVPAVAGSPDD-DDD 440

Human   454 DQNELASTNDSQLGFLPEAEMFS-------------LKTILSPKNMEPSKISGLIVNISTSLIAV 505
            |..::||.:..... .|.:||..             |:.:|.  ..||    |.:|:::..|...
  Fly   441 DDEDVASQSSMDTS-SPTSEMIEEVLAGRLKAQFRCLEPLLG--RFEP----GSVVSVAVMLFIF 498

Human   506 LIITFCIVTVLGREALTKGALWAVFLLAGSALLCAVVTGVIWRQPESKTKLSFKVPFLPVLPILS 570
            |....|:...:....|..|..||:.:.............||....::...|.||||.:|.:|.|.
  Fly   499 LSFAICVELKVSWTQLYTGTWWALIIYGFIIFAAGTCVAVIAVHNQNTRGLIFKVPLVPFVPALG 563

Human   571 IFVNVYLMMQLDQGTWVRFAVWMLIGFIIYFGYGLWHSEEASL 613
            ||.|:.||:.||..|||||.||:.||.::||.||:.:|:|..:
  Fly   564 IFCNILLMVHLDAVTWVRFFVWVCIGMVVYFLYGIRNSKEGEV 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC7A1	NP_003036.1	2A0303	4..610	CDD:273330	252/623 (40%)
CG13248	NP_649219.1	2A0303	32..603	CDD:273330	246/603 (41%)