Protein Alignment SLC7A1 and mnd

DIOPT Version :10

• Sequence 1: NP_003036.1
• Gene: SLC7A1 / 6541
• HGNCID: 11057
• Length: 629
• Species: Homo sapiens
• Sequence 2: NP_524074.1
• Gene: mnd / 39625
• FlyBaseID: FBgn0002778
• Length: 499
• Species: Drosophila melanogaster
• Alignment Length: 537
• Identity: 113/537 - (21%)
• Similarity: 210/537 - (39%)
• Gaps: 144/537 - (26%)

Human    27 RLSRCLNTFDLVALGVGSTLGAGVYVLAGAVAR--ENAGPAIVISFLIAALASVLAGLCYGEFGA 89
            :|.:.:...|.||:.||..:|:|::|....|.:  .:.|.:::: ::::.:.|::..|||.|.|.
  Fly    38 KLKKQIGLLDGVAIIVGVIVGSGIFVSPKGVLKFSGSIGQSLIV-WVLSGVLSMVGALCYAELGT 101

Human    90 RVPKTGSAYLYSYVTVGELWAFITGWNLILSYIIGTSSVARAWSATFDELIGRPIGEFSRTHMTL 154
            .:||:|..|.|.....|.|.||:..| :.|..::.|.:...|  .||...:.:|...      :.
  Fly   102 MIPKSGGDYAYIGTAFGPLPAFLYLW-VALLILVPTGNAITA--LTFAIYLLKPFWP------SC 157

Human   155 NAPGVLAENPDIFAVIIILILTGLLTLGVKESAMVNKIFTCINVLVLGFIMVSG---FVKGSVKN 216
            :||   .|...:.|..:|.:||.:....||....|..|||...|:.|..|:.:|   ...|:.::
  Fly   158 DAP---IEAVQLLAAAMICVLTLINCYNVKWVTRVTDIFTGTKVVALLVIVGAGVWWLFDGNTEH 219

Human   217 WQLTEEDFGNTSGRLCLNNDTKEGKPGVGGFMPFGFSGVLSGAATCFY----AFVGFDCIATTGE 277
            |.                      .|..||....|:      .|..||    ::.|::.:....|
  Fly   220 WD----------------------NPFSGGLQDPGY------IALAFYSGLFSYSGWNYLNFVTE 256

Human   278 EVKNPQKAIPVGIVASL-------LICFIAYFGV----------SAALTL---MMPYFCLDNNSP 322
            |:|:|.:.:|..|..|:       :|..||||.|          :.|:|.   |:.|
  Fly   257 ELKDPYRNLPKAICISMPVVTVIYMITNIAYFSVLSPDEILSSDAVAVTFGDKMLGY-------- 313

Human   323 LPDAFKHVGWEGAKYAVAVGSLCALSASLLGSMFPMPRVIYAMAEDGLLFKFLANVNDRTKTPII 387
                   :.|. ..:|||    |:...||.|::|...|:.:..|.:|.|...::.:|....||:.
  Fly   314 -------MSWI-MPFAVA----CSTFGSLNGAIFASSRLFFVGARNGHLPAAISLINVNCLTPVP 366

Human   388 ATLASGAVAAVMAFLFDLKDLVDLMSIGTLLAYSLVAACVLVLRYQPEQPNLVYQMASTSDELDP 452
            :.:..|.:..::.|:.|:..|::.:|....|...:..:.:|.:||:
  Fly   367 SLIFLGVLTLLLLFIEDVYVLINYVSYVEALFTLISVSGLLWMRYK------------------- 412

Human   453 ADQNELASTNDSQLGFLPEAEMFSLKTILSPKNMEPSKISGLIVNISTSLIAVLIITFCIVTVLG 517
                                         .||...|.|     ||::..:|.:::..|.::....
  Fly   413 -----------------------------QPKTERPIK-----VNLALPIIYLIVCLFLVIFSCT 443

Human   518 REALTKGALWAVFLLAG 534
            :.....| :..:.:|:|
  Fly   444 QTPYVVG-IGTIIILSG 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC7A1	NP_003036.1	2A0303	4..610	CDD:273330	113/537 (21%)
mnd	NP_524074.1	2A0308	22..496	CDD:273332	113/537 (21%)