Protein Alignment SLC7A1 and JhI-21

DIOPT Version :10

• Sequence 1: NP_003036.1
• Gene: SLC7A1 / 6541
• HGNCID: 11057
• Length: 629
• Species: Homo sapiens
• Sequence 2: NP_609542.1
• Gene: JhI-21 / 34624
• FlyBaseID: FBgn0028425
• Length: 500
• Species: Drosophila melanogaster
• Alignment Length: 512
• Identity: 121/512 - (23%)
• Similarity: 212/512 - (41%)
• Gaps: 117/512 - (22%)

Human    24 EETRLSRCLNTFDLVALGVGSTLGAGVYVLAGAV--ARENAGPAIVISFLIAALASVLAGLCYGE 86
            |:..|.|.|...:.||:.||:.:|:|:::....|  ..|:.|.:::| :|...:.|.:..|||.|
  Fly    33 EKIVLKRKLTLINGVAIIVGTIIGSGIFIAPTGVFIYTESVGSSLLI-WLTCGILSTIGALCYAE 96

Human    87 FGARVPKTGSAYLYSYVTVGELWAFITGWNLILSYIIGTSSVARAWSATFDELIGRPIGEFSRTH 151
            .|..:.::|..|.|..|:.|.|..|:..|..:|.....|.::.   :.:|.....:|.  |....
  Fly    97 LGTCITRSGGDYAYLLVSFGPLVGFLRLWIALLIIRPTTQTIV---ALSFAHYAVKPF--FPECD 156

Human   152 MTLNAPGVLAENPDIFAVIIILILTGLLTLGVKESAMVNKIFTCINVLVLGFIMVSG---FVKGS 213
            ...||..:|       |.|.:.:||.:..|.||.|..|..:||...:|.|..|::||   ...|.
  Fly   157 PPQNAVKLL-------AAICLTLLTTINCLSVKVSMKVQDVFTVGKLLALIMIILSGLYYMATGE 214

Human   214 VKN----WQ--LTEEDFGNTSGRLCLNNDTKEGKPGVGGFMPFGFSGVLSGAATCFYAFVGFDCI 272
            ::|    |:  .|..:.|...                       :||:        :||.|::.:
  Fly   215 LENFRNPWEGIYTARNIGYAF-----------------------YSGL--------FAFGGWNYL 248

Human   273 ATTGEEVKNPQKAIPVGIVASLLICFIAYFGVSAALTLMMPYFCLDNNSPLPDAFKHVGWEGAKY 337
            ....||:::|.|.:|..|..::.:....|..|:.|      ||.:.|.   |:..       :..
  Fly   249 NFVTEELQDPYKNLPRAIWIAMPLVTSIYVLVNLA------YFAVVNK---PEML-------SSL 297

Human   338 AVAV-------GSLC-------ALS--ASLLGSMFPMPRVIYAMAEDGLLFKFLANVNDRTKTPI 386
            ||||       |.|.       |||  ..:.|.:|...|:....|::|.|.||....:.:.:|||
  Fly   298 AVAVTFGNRVFGPLAFMVPIFVALSTFGGVNGVLFTSARLFATGAQEGHLPKFFQLFHVKQQTPI 362

Human   387 IATLASGAVAAVMAFLFDLKDLVDLMSIGTLLAYSLVA--ACVLVLRY-QPEQPNLVYQMASTSD 448
            .:.:.:..::.:|....::..|::..|  ::|..|:||  |.:|.||: :|:.|..:
  Fly   363 PSLIFTCLMSLLMLLTDNVYQLINYFS--SVLWLSVVASIAGMLWLRHKRPDLPRPI-------- 417

Human   449 ELDPADQNELASTNDSQLGFLPEAEMFSLKTILSPKNMEPSKISGLIVNISTSLIAV 505
                  :..||         ||...|.|..|::...|:|..:  .|::.|..:|..:
  Fly   418 ------KVHLA---------LPITFMVSCVTLVLLPNLEEPQ--NLLIGIGITLAGI 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC7A1	NP_003036.1	2A0303	4..610	CDD:273330	121/512 (24%)
JhI-21	NP_609542.1	2A0308	27..494	CDD:273332	121/512 (24%)