Protein Alignment SLC6A13 and slc6a13

DIOPT Version :10

• Sequence 1: NP_057699.2
• Gene: SLC6A13 / 6540
• HGNCID: 11046
• Length: 602
• Species: Homo sapiens
• Sequence 2: NP_001072913.1
• Gene: slc6a13 / 780375
• XenbaseID: XB-GENE-5947897
• Length: 601
• Species: Xenopus tropicalis
• Alignment Length: 607
• Identity: 478/607 - (78%)
• Similarity: 528/607 - (86%)
• Gaps: 11/607 - (1%)

Human     1 MDSRVSGTTSNGE-TKPVYPVMEK--KEEDG--TLERGHWNNKMEFVLSVAGEIIGLGNVWRFPY 60
            ||::|.|..|||. ..|..|:|||  |.|||  .:|||.||||:|||||||||||||||||||||
 Frog     1 MDNKVPGAVSNGYCVPPTKPLMEKEPKMEDGDMMIERGQWNNKVEFVLSVAGEIIGLGNVWRFPY 65

Human    61 LCYKNGGGAFFIPYLVFLFTCGIPVFLLETALGQYTSQGGVTAWRKICPIFEGIGYASQMIVILL 125
            |||||||||||||||:||||||||||.||||||||||||||||||||||:||||||:||:||:||
 Frog    66 LCYKNGGGAFFIPYLIFLFTCGIPVFFLETALGQYTSQGGVTAWRKICPLFEGIGYSSQVIVMLL 130

Human   126 NVYYIIVLAWALFYLFSSFTIDLPWGGCYHEWNTEHCMEFQKTNGSLNGTSENATSPVIEFWERR 190
            |.|||:||||||||||:|||.:|||..|.|.||||:|::|.|.|.:.|.|. |.||.||||||||
 Frog   131 NCYYIVVLAWALFYLFNSFTSELPWASCGHSWNTENCLDFYKGNSTHNVTL-NGTSSVIEFWERR 194

Human   191 VLKISDGIQHLGALRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVVLLIRGVTL 255
            ||:|||||.::|.|.|||||||||||:||||||||||||||||||||||||||||:|||||||:|
 Frog   195 VLRISDGIDNIGGLHWELALCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYLMLIVLLIRGVSL 259

Human   256 PGAAQGIQFYLYPNLTRLWDPQVWMDAGTQIFFSFAICLGCLTALGSYNKYHNNCYRDCIALCFL 320
            |||..||||||||:|:||.|||||||||||||||:||||||||||||||||:|||||||:|||||
 Frog   260 PGALTGIQFYLYPDLSRLQDPQVWMDAGTQIFFSYAICLGCLTALGSYNKYNNNCYRDCVALCFL 324

Human   321 NSGTSFVAGFAIFSILGFMSQEQGVPISEVAESGPGLAFIAYPRAVVMLPFSPLWACCFFFMVVL 385
            |||||||||||||||||||::||||.||:|||||||||||||||||.|:||||||||.|||||:|
 Frog   325 NSGTSFVAGFAIFSILGFMAEEQGVHISDVAESGPGLAFIAYPRAVSMMPFSPLWACFFFFMVIL 389

Human   386 LGLDSQFVCVESLVTALVDMYPHVFRKKNRREVLILGVSVVSFLVGLIMLTEGGMYVFQLFDYYA 450
            ||||||||||||||||:|||||.:||||||||:||||||::||||||||||||||||||||||||
 Frog   390 LGLDSQFVCVESLVTAVVDMYPTIFRKKNRRELLILGVSMISFLVGLIMLTEGGMYVFQLFDYYA 454

Human   451 ASGMCLLFVAIFESLCVAWVYGAKRFYDNIEDMIGYRPWPLIKYCWLFLTPAVCTATFLFSLIKY 515
            |||||||||||||:|||.|||||..|||.:|.||||||..:|||||||:|||||.|||||||:||
 Frog   455 ASGMCLLFVAIFETLCVGWVYGADNFYDKVEHMIGYRPTGIIKYCWLFVTPAVCMATFLFSLVKY 519

Human   516 TPLTYNKKYTYPWWGDALGWLLALSSMVCIPAWSLYRLGTLKGPFRERIRQLMCPAEDLPQRNPA 580
            |||||||.|.|||||||:|||||||||||||.|..|:|.|:||...||.|||..|..||||:...
 Frog   520 TPLTYNKHYVYPWWGDAIGWLLALSSMVCIPLWVGYKLSTIKGSLMERFRQLTFPDPDLPQKTQC 584

Human   581 GPSAPATPRTSLLRLTELESHC 602
            .|.: .|.:.:||.    ||.|
 Frog   585 EPLS-QTAQGTLLE----ESLC 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC6A13	NP_057699.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22		9/21 (43%)
		SLC6sbd_GAT2	32..575	CDD:271396	451/542 (83%)
slc6a13	NP_001072913.1	SLC5-6-like_sbd	37..579	CDD:444915	451/542 (83%)