Protein Alignment SLC6A11 and List

DIOPT Version :9

• Sequence 1: NP_055044.1
• Gene: SLC6A11 / 6538
• HGNCID: 11044
• Length: 632
• Species: Homo sapiens
• Sequence 2: NP_611364.2
• Gene: List / 37157
• FlyBaseID: FBgn0034381
• Length: 564
• Species: Drosophila melanogaster
• Alignment Length: 574
• Identity: 197/574 - (34%)
• Similarity: 302/574 - (52%)
• Gaps: 55/574 - (9%)

Human    16 EEARESEAPGGGCSSGGAAPARHPRVKRDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLC 80
            |.:::||.|       ...||.              .|.|.:||:.|.....:||||:|||||:.
  Fly     5 EISKKSEKP-------AEKPAE--------------QWGNGLEFLFSCISLSVGLGNIWRFPYIA 48

Human    81 YKNGGGAFLIPYVVFFICCGIPVFFLETALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNV 145
            ::||||.|:|||::..:..|.||::||.:|||||..|.:..: .:.||.:|:.....:..|....
  Fly    49 FQNGGGTFVIPYLIALLVIGRPVYYLEISLGQFTGRGVVKAF-DMAPLLKGVALGQVLATAASIT 112

Human   146 YYIIILAWAI-FYLSNCFTTELPWATCGHEWNTENCVEFQKLNVSNYSHVSLQNATSPVMEFWE- 208
            ||..|:|..: |:|:: |.:||||:.|...|.|: |.:....|.|        ...||...::|
  Fly   113 YYSSIMALTLRFWLAS-FGSELPWSRCWESWGTD-CHDGNAQNSS--------GKMSPAQLYFER 167

Human   209 ---HRVLAISDGIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLILLI 270
               |.|..|.:|:. :.|  |:|..||..||.:....:.:|.||:||..|....|||::|||||:
  Fly   168 EILHEVPNIDNGLS-LPN--WQLVACLAIAWLVIGGVLIRGIKSSGKAAYFLGVFPYVVLLILLL 229

Human   271 RGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNNYNNNCYRDCI 335
            |.||||||.:||.::..|....|.:|.||..|.||:|||.|||.|.|....||||:|.|.|.|.:
  Fly   230 RAVTLPGAIDGIIYFFKPQWRELLNPLVWYAAVTQVFFSLAICFGTLITYASYNNFNRNVYNDIV 294

Human   336 MLCCLNSGTSFVAGFAIFSVLGFMAYEQGVP-IAEVAESGPGLAFIAYPKAVTMMPLSP-LWATL 398
            ::..::|.:|.:||...|.:||.:|.|.|.| |..|.:.|.|||||:||:|:......| ::|.|
  Fly   295 IITTMDSCSSIIAGCITFGILGNLARETGNPDIGSVVKGGAGLAFISYPEAIAKFEYVPQMFAVL 359

Human   399 FFMMLIFLGLDSQFVCVESLVTAVVDMY----PKVFRRGYRRELLILALSVISYFLGLVMLTEGG 459
            ||:||..||:.|.......::..:.|.:    |.:::       |...|:|:.:.:.:|.:|.||
  Fly   360 FFLMLFVLGIGSTVGMGSCILRVIRDQFGLRSPPIWK-------LASGLTVLGFSVSIVYMTPGG 417

Human   460 MYIFQLFDSYAASGMCLLFVAIFECICIGWVYGSNRFYDNIEDMIGYRPPSLIKWCWMIMTPGIC 524
            .:|..|.|.|..| ...|.:||.|.:.:.|:||.|||.::|:.|:|.......:.||..:|||:.
  Fly   418 QFILNLVDFYGVS-FTALILAIGELVAVAWIYGVNRFCEDIKFMMGIETGWYWRLCWRFITPGLM 481

Human   525 AGIFIFFLIKYKPLKYNNIYTYPAWGYGIGWLMALSSMLCIPLWICITVWKTEG 578
            ..:.|:.|:....|:|..: .||...:..|..:|...::.:|.|....::|..|
  Fly   482 TAVLIYMLLDMSALEYKGV-GYPTLAHVFGCFLATLGLIQLPGWAIYAIYKKRG 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC6A11	NP_055044.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..41		6/24 (25%)
		SLC6sbd_GAT3	49..590	CDD:212077	191/541 (35%)
List	NP_611364.2	SLC6sbd	19..489	CDD:271359	180/505 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820