Protein Alignment SLC6A9 and CG8850

DIOPT Version :9

• Sequence 1: NP_964012.2
• Gene: SLC6A9 / 6536
• HGNCID: 11056
• Length: 706
• Species: Homo sapiens
• Sequence 2: NP_725122.2
• Gene: CG8850 / 36331
• FlyBaseID: FBgn0033708
• Length: 629
• Species: Drosophila melanogaster
• Alignment Length: 638
• Identity: 211/638 - (33%)
• Similarity: 347/638 - (54%)
• Gaps: 60/638 - (9%)

Human    62 HGAYNSGLLPQLMAQHSLAMAQNGAVPSEAT-KRDQNLKRGNWGNQIEFVLTSVGYAVGLGNVWR 125
            |...|.|:...:.:.....:..|....||:: :|||      |...:||:.:.:..:||||||||
  Fly    24 HPGSNDGISTVIYSAEGEELTINCEAESESSGQRDQ------WSRGVEFLFSCIALSVGLGNVWR 82

Human   126 FPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVWRISPMFKGVGYGMMVVST 190
            ||::...||||||:.||.|:|:..|.|::::|:..|||:|:||:..:.::|:.:|:.||.:..:.
  Fly    83 FPFIALENGGGAFLIPYVIVLLLIGRPVYYLEVIIGQFSSRGCIRAFDMAPIMRGIAYGQVYSTA 147

Human   191 YIGIYYNVVICIAFYYFFSSMTHVLPWAYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLL 255
            ....||..::.:...|..:|.:.||||.||...|. ..|.    |:..|     ||..|::
  Fly   148 LATTYYACIMALTIRYLVASFSEVLPWTYCLVEWG-KSCV----ATGAT-----AANDSSI---- 198

Human   256 NHSLQRTSPSEEYWRLYVLKLSD--DIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYF 318
               :|..|.:|.::...||:..:  |....|.....|:.||..:|:::...|.:|::||||..||
  Fly   199 ---VQGVSSAELFFTQTVLREPESLDDNGLGTPSWDLVLCLLATWVIIGTILSKGIRSSGKASYF 260

Human   319 TATFPYVVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMA 383
            .|.||||::.:|.:|.|||.||:.||:|:|.|||.::|...||..|.:|:|:||...:|.|:..|
  Fly   261 LALFPYVIMIVLLIRAVTLPGAWQGIVYFLKPQWSQLLNPHVWYAAITQMFFSLAICFGTLVMYA 325

Human   384 SYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGV-DVSRVADHGPGLAFVAYPEA 447
            |:|.|:.|.::|.:||:..:..||:.||.:||.|||.:|..... |:|:|...|.||||::||||
  Fly   326 SFNDFNKNVHKDVIIITTIDSLTSILAGCIIFGILGNLAFETNTKDISQVVKGGAGLAFISYPEA 390

Human   448 LTLLPISP-LWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGN--EWILQKKTYVTLGVAVAGF 509
            :......| |:::||||||::||:|:...:...:|..:.|...:  .|:|      .:..::.||
  Fly   391 IAKFKYLPQLFAVLFFFMLLVLGIGSNIGMASAVVNVVKDRFTHLPHWLL------AVSASIIGF 449

Human   510 LLGIPLTSQAGIYWLLLMDNYAASFSLVVISCIMCVAIMYIYGHRNYFQDIQMMLGFPPPLFFQI 574
            |.|:...:..|.:.|.|:|.|..:|..:|::....:|:.:|||.:....||:.||......:::|
  Fly   450 LCGLVYMTPGGQFVLNLVDFYGCTFIALVLAIAELLAVGWIYGVKRICSDIEFMLNVKTSFYWRI 514

Human   575 CWRFVSPAIIFFILVFTVIQYQPITYNHYQYP------GWAV-AIGFLMALSSVLCIPLYAMFRL 632
            ||..|:|.::|.:||:.:..|:|:||...|||      ||.: .:|       ||.:|.:|:..:
  Fly   515 CWAIVAPGLMFLVLVYMLFSYEPLTYRGVQYPPVYYMAGWIIWGLG-------VLQLPFWALVTI 572

Human   633 CRTDGDTLLQRLKNATKPSRDWGP-------ALLEHRTGRYAPTIAPSPEDGF 678
            .:..|.|...:...|.:|:.:|||       |.:.||. |.|.  ..||..|:
  Fly   573 YQQPGKTFGSKFGLAMQPTANWGPLQTQKFEAYIIHRK-READ--FKSPRGGY 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC6A9	NP_964012.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..26
		SLC6sbd_GlyT1	84..667	CDD:212067	204/603 (34%)
CG8850	NP_725122.2	SLC6sbd	58..532	CDD:271359	175/502 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820