Protein Alignment SLC6A9 and snf-7

DIOPT Version :9

• Sequence 1: NP_964012.2
• Gene: SLC6A9 / 6536
• HGNCID: 11056
• Length: 706
• Species: Homo sapiens
• Sequence 2: NP_499702.2
• Gene: snf-7 / 176723
• WormBaseID: WBGene00004906
• Length: 705
• Species: Caenorhabditis elegans
• Alignment Length: 658
• Identity: 199/658 - (30%)
• Similarity: 320/658 - (48%)
• Gaps: 100/658 - (15%)

Human    95 DQNLKRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMELS 159
            |:...||     ||..|:|:|.||||||:||||...|:|||.:|:..|.:..|...:|...||.:
 Worm    65 DRQAFRG-----IESFLSSLGQAVGLGNIWRFPTTAYKNGGLSFLIAYVVCGILFAVPAIHMEFA 124

Human   160 FGQFASQGCLGVW-RISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAYCNNP 223
            .||:|::.....: |:.|:.:|||:...:|...||:||.:||.....|.| ::.:....:.|||.
 Worm   125 LGQYAAKSPPAAFRRMMPILEGVGWMTCLVGAIIGVYYMIVISWIVLYLF-NIIYATKISKCNND 188

Human   224 WNTHD------------CAGVLDASNL--TNGSRPAALPSNLSHLLNHSLQRTS-----PSEEYW 269
            ||.:.            |:|.:..|:|  ||.:|.|::.|.:.::.......|:     .:|:::
 Worm   189 WNKNRSTICYEGVKQKLCSGYMLNSSLVMTNLTRNASVHSKMMYIDGKCQNATNMKLAVGTEQFF 253

Human   270 RLYVLKLSDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRG 334
            ..:|:|.|....:|..:.:|:|..:.|.|::..:.||||:|:.||:.|:|...||.::..|.:||
 Worm   254 TNFVVKPSTGFTDFNSINVPMLAAVAVCWVIAIISLIRGMKAIGKLSYYTVLLPYAIIIALMIRG 318

Human   335 VTLEGAFDGIMYYLTPQWDK-----------ILEAKVWGDAASQIFYSLGCAWGGLITMASYNKF 388
            :|||||..|:.:..   |.|           :.:..||..|..|:.:||....|||:.:.||||.
 Worm   319 LTLEGASTGLHFLF---WGKPNEYGHYDFAGLYDPDVWIAALMQMCFSLSIGQGGLMNIGSYNKK 380

Human   389 HNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVS------RVADHGPGLAFVAYPEA 447
            ..|.|||:.::.:.:...|:..|..:||.|||:|....:.:|      .|...|..|||:.|.||
 Worm   381 TYNWYRDAYLVVLCDTLMSLLGGTAVFSTLGFLAEQRNISISNPKGFNEVVQEGHALAFIVYTEA 445

Human   448 LTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQKKTYVTLGVAVAGFLLG 512
            :..:|...||..|||.||.|||:.|:..::||:.:.:.|..  .::.|.:....:.|:...||||
 Worm   446 IAQMPYPFLWYALFFVMLFLLGISTEIVIIETVCSCLADRF--HYLRQHRWITVVTVSTTFFLLG 508

Human   513 IPLTSQAGIYWLLLMDNYAASFSLVVISCIMCVAIMYIYGHRNYFQDIQMM-----------LGF 566
            :.:||.||.||..|.|.|:|..|..:.:.|||:.:.:.||..|:..||:.|           ||
 Worm   509 LVMTSDAGFYWFDLYDEYSAGVSATIGTAIMCLTVCWCYGLDNFRADIREMWEEPESRLDKYLG- 572

Human   567 PPPLFFQICWRFVSPAIIFFILVFTVI--QYQPITYNHYQYPGWAVAIGFLMALSSVLCIPLYAM 629
            |....:.|.||||:| |...:::|..|  :..|...:..:||....|.|:.:|......:|::|.
 Worm   573 PGAYVWTIVWRFVTP-ICCLVIMFAWIWDKKYPFKGDSKKYPPVFDAFGWFVAALPFFVVPVFAG 636

Human   630 FRLCRTDGDTLLQRLKNATKPSR--------------------DWGPALLEHRTGRYAPTIAPSP 674
            |         .::|.|:...|.|                    :|     :.:.|...|.:.|..
 Worm   637 F---------AIKRFKDLNIPIRGVFMVQKQHPAYDRISEKWPEW-----KQKIGDKLPELEPGE 687

Human   675 ---EDGFE 679
               |||.|
 Worm   688 DDLEDGLE 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC6A9	NP_964012.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..26
		SLC6sbd_GlyT1	84..667	CDD:212067	193/641 (30%)
snf-7	NP_499702.2	SLC6sbd	70..598	CDD:271359	176/540 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820