Protein Alignment SLC6A7 and GlyT

DIOPT Version :9

• Sequence 1: XP_016865256.1
• Gene: SLC6A7 / 6534
• HGNCID: 11054
• Length: 754
• Species: Homo sapiens
• Sequence 2: NP_611836.2
• Gene: GlyT / 37772
• FlyBaseID: FBgn0034911
• Length: 1188
• Species: Drosophila melanogaster
• Alignment Length: 646
• Identity: 281/646 - (43%)
• Similarity: 405/646 - (62%)
• Gaps: 54/646 - (8%)

Human   118 RGNWTGKLDFLLSCIGYCVGLGNVWRFPYRAYTNGGGAFLVPYFLMLAICGIPLFFLELSLGQFS 182
            ||.|||:.|||||.:||.|||||||||||..|.|||||||:|:.:||.|.|:||.|:|||.||::
  Fly    57 RGTWTGRFDFLLSLLGYSVGLGNVWRFPYLCYNNGGGAFLIPFTIMLVIAGLPLMFMELSFGQYA 121

Human   183 SLGPLAVW-KISPLFKGAGAAMLLIVGLVAIYYNMIIAYVLFYLFASLTSDLPWEHCGNWWNTEL 246
            :|||:||: :..|||:|.|..|:|:..:|.:|||:|||:.:||:|||....|||::|...|:|:.
  Fly   122 ALGPVAVYRRFCPLFRGLGTGMILVSAIVMLYYNLIIAWTIFYMFASFAPVLPWQNCEPAWSTKY 186

Human   247 CLEHRVSKDGNGALPLNLTCTVSPSEEYWSQTH--TEAEEEGRRGRVVSNSYPQVIF--LPQPPK 307
            |..:..:..          |..:....|....|  |.|.|         |:...:..  |.:||
  Fly   187 CFSYAQADQ----------CEATNGTYYLRTCHNATSAAE---------NNITTLALGALKRPP- 231

Human   308 AEEGVSRYVLHIQGSQGIGSPGEIRWNLCLCLLLAWVIVFLCILKGVKSSGKVVYFTATFPYLIL 372
            |||..:.:||.:  |:||...|.|:.:|..||.|||.|||||:.|||:||||||||||.|||::|
  Fly   232 AEEYFNNFVLGL--SKGIEETGSIKLSLAACLFLAWTIVFLCLCKGVQSSGKVVYFTALFPYVVL 294

Human   373 LMLLVRGVTLPGAWKGIQFYLTPQFHHLLSSKVWIEAALQIFYSLGVGFGGLLTFASYNTFHQNI 437
            ::|.|||||||||..||.|||||.:..|.:::||.:||:|||::|...:|||:|.:|||.|..|.
  Fly   295 VILFVRGVTLPGASTGILFYLTPDWKQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNC 359

Human   438 YRDTFIVTLGNAITSILAGFAIFSVLGYMSQELGVPVDQVAKAGPGLAFVVYPQAMTMLPLSPFW 502
            |:|:.||...|..||..||..|||::|:::.||.|.|::|...|.||||:|||:.:|.||:||.|
  Fly   360 YKDSLIVAFCNIATSFFAGLVIFSIIGFLAHELNVDVEKVVDQGAGLAFIVYPEVVTRLPVSPVW 424

Human   503 SFLFFFMLLTLGLDSQFAFLETIVTAVTDEFPYYLRPKKAVFSGLICVAMYLMGLILTTDGGMYW 567
            :.|||.||||||||||||.:||:.||:.|.|| .||..|......:.:..|:.||..||:.||||
  Fly   425 AVLFFVMLLTLGLDSQFALMETVTTAILDRFP-NLRQYKIWVVLSVAIFGYIGGLGFTTNSGMYW 488

Human   568 LVLLDDYSASFGLMVVVITTCLAVTRVYGIQRFCRDIHMMLGFKP---GLYFRACWLFLSPATLL 629
            |.|:|.|:|::.::::.|:.|:.:..:||.|||..||..|:|.:.   ..::...|.:::|||||
  Fly   489 LQLMDKYAANWSVLLIAISECILIAWIYGSQRFLNDIQGMIGKRSWFWNFFWGIMWRYITPATLL 553

Human   630 ALMVYSIVKYQPSEYGSYRFPPWAELLGILMGLLSCLMIPAGMLVA---VLREEGSL--WERLQQ 689
            .::.::.|:|:|::||.|.:|.||:.:|.::|||..|:|   .|||   :.|...||  .:|::.
  Fly   554 FILFFNWVEYKPAKYGHYVYPMWADAVGWIVGLLPVLVI---FLVAFQEIWRAPMSLSFRDRIKH 615

Human   690 ASRPAMDWGPSLEENRTGMYVATLAGSQSPKPLMVHMRKYGGITSFENTAIEVDREIAEEE 750
            ..:|..:|||:      |.....|...:      ...:.|.|:|   ||.|.::.|.:.::
  Fly   616 LLQPTAEWGPA------GRPCVNLHAER------YQSQNYDGVT---NTKILIEEEASPKQ 661

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC6A7	XP_016865256.1	None
GlyT	NP_611836.2	SNF	57..603	CDD:249680	264/571 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100873
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.720