DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rnf130 and rnf130

DIOPT Version :9

Sequence 1:	XP_038942740.1	Gene:	Rnf130 / 652955	RGDID:	1562041	Length:	439	Species:	Rattus norvegicus
Sequence 2:	NP_001107712.1	Gene:	rnf130 / 100124963	XenbaseID:	XB-GENE-949564	Length:	419	Species:	Xenopus tropicalis

Alignment Length:	404	Identity:	311/404 - (76%)
Similarity:	341/404 - (84%)	Gaps:	1/404 - (0%)

- Green bases have known domain annotations that are detailed below.

  Rat    12 LAALALLTCSLWPTRADNASQEYYTALINVTVQEPGRGTPLTFRIDRGRYGLDSPKAEVRGQVLA 76
            |..|.|..||:..:.:|.|:.|.|:||:|||:|:|. ..|:..|||.|||||||||.|.:|.:|.
Frog    13 LPILVLFPCSMVQSGSDTANMENYSALVNVTIQDPS-SNPVLLRIDGGRYGLDSPKTEAKGLLLT 76

  Rat    77 PLPIHGVADHLGCDPQTRFFVPPNIKQWIALLQRGNCTFKEKISRAAFHNAVAVVIYNNKSKEEP 141
            |:.|||.||.|||||||||.||||.|.||||||||||||||||.|||.|||.|||||||.||||.
Frog    77 PVHIHGAADRLGCDPQTRFNVPPNTKHWIALLQRGNCTFKEKILRAASHNASAVVIYNNNSKEET 141

  Rat   142 VTMTHPGTGDIIAVMITELRGKDILSYLEKNISVQMTIAVGTRMPPKNFSRGSLVFVSISFIVLM 206
            |||||.|||:|:|:||:|.||::||||:|:||||.|.||||:|...|||||||||||||||||||
Frog   142 VTMTHQGTGEIVAIMISEARGREILSYVERNISVLMAIAVGSRNQHKNFSRGSLVFVSISFIVLM 206

  Rat   207 IISSAWLIFYFIQKIRYTNARDRNQRRLGDAAKKAISKLTTRTVKKGDKETDPDFDHCAVCIESY 271
            ||||||||||||||||||:|||||||||||||||||.||||||||||||||||||||||||||||
Frog   207 IISSAWLIFYFIQKIRYTSARDRNQRRLGDAAKKAIGKLTTRTVKKGDKETDPDFDHCAVCIESY 271

  Rat   272 KQNDVVRVLPCKHVFHKSCVDPWLSEHCTCPMCKLNILKALGIVPNLPCTDNVAFDMERLTRTQA 336
            ||||:||||||||||||.|||||||||||||||||||||||||..|:|||||||||||||||:|.
Frog   272 KQNDIVRVLPCKHVFHKVCVDPWLSEHCTCPMCKLNILKALGIAANVPCTDNVAFDMERLTRSQP 336

  Rat   337 VNRRSALGDLANDSSLGLEPLRTSGISPLPQDGELTPRTGEINIAVTKEWFIIASFGLLSALTLC 401
            .:||||..|...:.||.||.||:|.||..|.|.|..||||||||:||||||||||||||||||||
Frog   337 PSRRSAPNDPTEEGSLSLESLRSSRISQGPHDVEAIPRTGEINISVTKEWFIIASFGLLSALTLC 401

  Rat   402 YMIIRATASLNANE 415
            ||||:|||||.|.|
Frog   402 YMIIKATASLYATE 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rnf130	XP_038942740.1	PA_GRAIL_like	40..179	CDD:239037	99/138 (72%)
		HRD1	<197..366	CDD:227568	145/168 (86%)
		RING-H2_RNF130	262..310	CDD:319717	45/47 (96%)
rnf130	NP_001107712.1	PA_GRAIL_like	41..179	CDD:239037	99/138 (72%)
		HRD1	<197..344	CDD:227568	135/146 (92%)
		RING_Ubox	262..310	CDD:388418	45/47 (96%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	170	1.000	Domainoid score	I17522
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H41267
Inparanoid	1	1.050	569	1.000	Inparanoid score	I6402
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	1	1.000	-	-		FOG0000832
OrthoInspector	1	1.000	-	-		otm65210
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X295
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.060