Protein Alignment SLC5A5 and CG32669

DIOPT Version :9

• Sequence 1: XP_011526494.1
• Gene: SLC5A5 / 6528
• HGNCID: 11040
• Length: 654
• Species: Homo sapiens
• Sequence 2: NP_727460.1
• Gene: CG32669 / 326229
• FlyBaseID: FBgn0052669
• Length: 604
• Species: Drosophila melanogaster
• Alignment Length: 581
• Identity: 218/581 - (37%)
• Similarity: 326/581 - (56%)
• Gaps: 55/581 - (9%)

Human    11 TFGAWDYGVFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPVGLSLSASFMSAVQVLG 75
            |.|||||.:.|::|::|..||::.....|.|.:..::....|.:...||..||.|||||||.:||
  Fly     3 TLGAWDYTILAVVLIISVAIGIYYRFVGGKQSTTTEYLLADRSMNVAPVAFSLMASFMSAVTILG 67

Human    76 VPSEAYRYGLKFLWMCLGQLLNSVLTALLFMPVFYRLGLTSTYEYLEMRFSRAVRLCGTLQYIVA 140
            |..|.|:||..|:.:.|..:|::.:.|.|.:||||||...|.|||||:||..|.||..:|.:.:.
  Fly    68 VSMENYQYGTMFVVINLSYVLSTPVAAYLIIPVFYRLKTASVYEYLELRFGYATRLAASLSFSLQ 132

Human   141 TMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMKAVVWTDVFQVVVMLSGFWVV 205
            .:||.|||:|||||.|..||||....|::..|::||||..:||||||:.||::|.::|.:..:.|
  Fly   133 MVLYMGIVVYAPALALEAVTGLSQVFSIVIVGVVCTFYATLGGMKAVLITDIYQSLLMFAAVFSV 197

Human   206 LARGVMLVGGPRQVLTLAQNHSRINLMDFNPDPRSRYTFWTFVVGGTLVWLSMYGVNQAQVQRYV 270
            :....:..|....:..:||.:.||||.:|:.||..|:|::|.::||...:|::|||||.||||.:
  Fly   198 IICAWVKAGSLEVIWRVAQENGRINLTNFSVDPTERHTWFTQILGGCATYLAIYGVNQTQVQRLM 262

Human   271 ACRTEKQAKLALLINQVGLFLIVSSAACCGIVMFVFYTDCDPLLLGRISAPDQLSGRLTPSSPQY 335
            |.::...|:.||......|.|:..|....|:.::.:|.||||||.||:::.||:
  Fly   263 AVKSLSAARAALWWCLPILCLLSLSTCFSGLCIYWYYRDCDPLLEGRVNSRDQV----------- 316

Human   336 MPLLVLDIFEDLPGVPGLFLACAYSGTLSTASTSINAMAAVTVEDLIKPRL-----RSLAPRKLV 395
            |||.|:|...:..|:.|||::..:..:|||.|:.|:::||||:||.:||.:     |:|..|:.:
  Fly   317 MPLFVVDTMGEYTGLAGLFVSGIFCASLSTISSIISSLAAVTLEDYLKPLVSCCAKRTLTDRQTL 381

Human   396 IISKGLSLIYGSACLTVAALSSLLGGGVLQGSFTVMGVISGPLLGAFILGMFLPACNTPGVLAGL 460
            ..||.|||.:|:.|:.:|.::..: ||:||.:.::.|:|.|||||.|.|||::...|..|.:.||
  Fly   382 WYSKLLSLFFGALCIGMAFMAGSI-GGLLQAALSIFGIIGGPLLGLFTLGMYVTKANEKGAIGGL 445

Human   461 GAGLALSLWVALGATLYPPSEQTMRVLPSSAARCVALSVNASGLLDPALLPANDSSRAPSSGMDA 525
            ...||...|:..|.. .||    :..|..|.|.|   .|:.|...|..|               .
  Fly   446 LISLAFCFWIGFGQP-KPP----LVSLDMSTAGC---PVDRSFARDIFL---------------K 487

Human   526 SRPALADS-----FYAISYLYYGALGTLTTVLCGALISCLTGPTKRSTLAPGLLWWDLARQ 581
            :..|:|:.     .|.|||::|.|||.|.|...|.|:|.|.          .||.||..|:
  Fly   488 TVIAVAEEEHYFYLYRISYMWYAALGFLITFFGGWLLSWLF----------ALLKWDNNRR 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC5A5	XP_011526494.1	SLC5sbd_NIS	15..565	CDD:271393	210/559 (38%)
CG32669	NP_727460.1	SLC5sbd_NIS-SMVT	7..527	CDD:271383	209/554 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	371	1.000	Domainoid score	I905
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	434	1.000	Inparanoid score	I1707
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D489472at33208
OrthoFinder	1	1.000	-	-		FOG0000151
OrthoInspector	1	1.000	-	-		mtm8669
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X112
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.870