Protein Alignment SLC5A4 and CG5687

DIOPT Version :9

• Sequence 1: XP_016884409.1
• Gene: SLC5A4 / 6527
• HGNCID: 11039
• Length: 689
• Species: Homo sapiens
• Sequence 2: NP_001286910.1
• Gene: CG5687 / 38255
• FlyBaseID: FBgn0035293
• Length: 683
• Species: Drosophila melanogaster
• Alignment Length: 555
• Identity: 126/555 - (22%)
• Similarity: 231/555 - (41%)
• Gaps: 124/555 - (22%)

Human    83 GTIGGFFLAGRDMAWWPMGASLFASNIGSNHYVGLAGTGAASGVATVTFEWTSSVMLLI------ 141
            |:....||.|.:|:.:|:..||..|.|.:...:|        ..:.:.|:.|..|:::|
  Fly   125 GSSSNEFLLGSEMSIFPVTLSLTTSFITAIELLG--------NPSEMYFQGTQFVLIVIPMVIVI 181

Human   142 --LGWIFVPIYIKSGVMTMPEYLKKRFGGERLQVYLSILSLFICVVLL---ISADIFAGAIFIKL 201
              ...||.|||.|..:.:..|||..|||.|     :.||...:.|:.:   .:..:.|.||.:..
  Fly   182 PVAVKIFYPIYFKMELTSCYEYLGIRFGKE-----IRILGAVLYVIQMCFYTAVAVLAPAIALSK 241

Human   202 ALGLDLYLAIFILLAMTAVYTTTGGLASVIYTDTLQTIIMLIGSFILMGFAFNEVGGYESFTEKY 266
            |.|||..:|:.::..:...|::.||:.:|:..|:.|..::.:...:::|     :|.:.|
  Fly   242 ATGLDTKIAVVLIYVVCVFYSSQGGMKAVVIADSFQAAVLAVSLVLIVG-----LGCFYS----- 296

Human   267 VNATPSVVEGDNLTI--SASCYTPRADSFHIFRDAVTGDIPWPGIIFGMPITALWYW----CTNQ 325
                     |:.:.:  :||.:. |.:.|::..|..|....|..:|.|     .:||    ||||
  Fly   297 ---------GNPIQVFQTASDHN-RLEFFNMDPDPTTRHTVWSVVIGG-----FFYWTSLFCTNQ 346

Human   326 VIVQRCLCGKDMSHVKAACIMCAYLKLLPMFLMVMPGMISRILYTDMVACVVPSECVKHCGVDVG 390
            ..||:|:..|.:...|.| :..|.:.|:.:||:        ..||.::.....::|.......:.
  Fly   347 ASVQKCMSLKSLRLAKIA-LGFAIIGLIVVFLL--------NFYTGLMVFTHYADCDPLTAGRIS 402

Human   391 CTNYAYPTMVLELMP--QGLRGLMLSVMLASLMSSLTSIFNSASTLFTIDLYTKMR--KQASEKE 451
            .|:...|..|:....  ..:.|:.::.:.|:.:.::.|..||.|.:...||.....  |.:.||.
  Fly   403 ATDQLLPYYVINTYEHISSVAGIFVAGIFAASLGTVASALNSLSAVTCEDLLVNGMNIKISPEKG 467

Human   452 LLIA------------GRIFVLLLTVVSIVWVPLVQVSQNGQLIHYTESISSYLGPPIAAVFVLA 504
            ...|            |.:|:               |...|.::..|.:::..:|.....:|||.
  Fly   468 ATYAKWMSLGFGIASFGLVFI---------------VEHLGGVLQATLTLNGLIGGVTLGLFVLG 517

Human   505 IFCKRVNEQGAFWGLMVGLAM----GLIRMITEFAYGTGSCLAPSNCPKIICGVHYLYFSIVLFF 565
            |.||:.|.:|||:|.::.||:    |::..|.......    .|::..|..|.|
  Fly   518 IACKQANTKGAFYGGLLSLALVIFVGVVAQIVSVEQPA----LPTSIDKCDCHV----------- 567

Human   566 GSMLVTLGISLLTKPIPDVH--------LYRLCWV 592
             :|...:| ||||:|:..:.        ::||.::
  Fly   568 -NMTNIIG-SLLTEPLEVIEEGGFTSWPIFRLSYM 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC5A4	XP_016884409.1	None
CG5687	NP_001286910.1	SLC5sbd_NIS-SMVT	99..620	CDD:271383	126/555 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810