Protein Alignment SLC5A4 and CG33124

DIOPT Version :9

• Sequence 1: XP_016884409.1
• Gene: SLC5A4 / 6527
• HGNCID: 11039
• Length: 689
• Species: Homo sapiens
• Sequence 2: NP_001097056.3
• Gene: CG33124 / 318891
• FlyBaseID: FBgn0053124
• Length: 588
• Species: Drosophila melanogaster
• Alignment Length: 585
• Identity: 131/585 - (22%)
• Similarity: 235/585 - (40%)
• Gaps: 150/585 - (25%)

Human    98 WPMGASLFASNIGSNHYVGLAGTGAASGVATVTFEWTSSVMLLIL-----GWIFVPIYIKSGVMT 157
            :|:..||.||.|.     |:|..|..|.:.....:::..|:.:::     .:|::|::....|.:
  Fly    71 FPVAMSLIASFIS-----GVAILGNPSEIYYYGTQYSLIVLAIVIQGLAVSYIYLPVFSALQVRS 130

Human   158 MPEYLKKRFGGERLQVYLSILS-LFICVVLLISA-DIFAGAIFIKLALGLDLYLAIFILLAMTAV 220
            ..|||..||.    .:..:|:| :|:..|||.:. .:|..|:.:..|.||::::...:::.:..:
  Fly   131 SYEYLGMRFH----PLIRNIVSIMFVIEVLLYTPFVVFVPALALNQASGLNIHMIEVLIIVVCVI 191

Human   221 YTTTGGLASVIYTDTLQTIIMLIGSFILMGFAFNEVGGYESFTEKYVNATPSVVEGDNL---TIS 282
            ||..|||.:|::||..|.:||.....::...|...:...:.|.|       |:|:|..|   .|:
  Fly   192 YTLLGGLKAVVHTDIWQVVIMFASVVVVAILATCYITDLDDFFE-------SLVDGGRLIFGNIN 249

Human   283 ASCYTPRADSFHIFRDAVTGDIPWPGIIFGMPITALWYW----CTNQVIVQRCLCGKDMS----- 338
            .|.|.         |:.|     |..:|.|     .:||    ..:|.:|.|.:...::.
  Fly   250 PSPYV---------RNTV-----WSVVIGG-----AFYWTSITAVHQTMVHRYMSLPNLKMARTS 295

Human   339 ---HVKAACIMCAYLKLLPMFLMVM-----PGMISRILYTDMVACVVPSECVKHCGVDVGCTNYA 395
               .|..:.|..:.|..|.:.:..|     |....:|:..|.   :||...|:..|       :.
  Fly   296 IAFFVLGSIIFYSVLSFLGLLIFNMYKDCDPLSAGQIMNNDQ---LVPLFVVQSVG-------HI 350

Human   396 YPTMVLELMPQGLRGLMLSVMLASLMSSLTSIFNSASTLFTIDLYT---KMRKQASEKELLIAGR 457
            |          |:.||.::.:..:.:|||:...||.|.:...|:..   ||:...:...:::...
  Fly   351 Y----------GIPGLFIAGIFGAGLSSLSVFLNSTSLVILQDIVRGCFKMQPGETASAIIVKAT 405

Human   458 IF---------VLLLTVVS---IVWVPLVQVSQNGQLIHYTESISSYLGPPIAAVFVLAIFCKRV 510
            |.         ||||..||   .:.:.||.:           :.||..|     :|.||:.....
  Fly   406 IVIMGALVFGEVLLLEKVSGILSICMSLVAI-----------ATSSTFG-----IFTLAVLVPWA 454

Human   511 NEQGAFWGLMVG-LAMGLIRMITEFAYGTGSC------LAPSNCP-------------KIICGVH 555
            |..|...|.:.| |..|.|...::.|..:|..      ::.::||             :.:..:.
  Fly   455 NTVGTAVGGIAGFLLTGWITFGSQIAAASGQLHHHRLPVSVASCPGNVTARENVWVDEEQVFPLF 519

Human   556 YLYFSIVLFFGSM-LVTLG--ISLLTKPI-----------PDVH--LYRLCWVLRN-STEERIDI 603
            .|.|..:...|:: :|.:|  :||:|||.           |.:|  |.:.|:..|| ...|..||
  Fly   520 RLSFHWINPIGALTVVVVGSLVSLVTKPTDIKSLDSDLISPVIHRFLPKECFKQRNLDKSEATDI 584

Human   604  603
              Fly   585  584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC5A4	XP_016884409.1	None
CG33124	NP_001097056.3	SLC5sbd_NIS-SMVT	9..533	CDD:271383	115/532 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146462
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750