Protein Alignment SLC5A3 and CG5687

DIOPT Version :9

• Sequence 1: NP_008864.4
• Gene: SLC5A3 / 6526
• HGNCID: 11038
• Length: 718
• Species: Homo sapiens
• Sequence 2: NP_001286910.1
• Gene: CG5687 / 38255
• FlyBaseID: FBgn0035293
• Length: 683
• Species: Drosophila melanogaster
• Alignment Length: 559
• Identity: 133/559 - (23%)
• Similarity: 229/559 - (40%)
• Gaps: 96/559 - (17%)

Human     2 RAVLDTADIAIVALYFILVMCIGFFAMWKSNRSTVSGYFLAGRSMTWVAIGASLFVSNIGSEHFI 66
            :|.....|..|:....::.:.||.|..:.....:.|..||.|..|:...:..||..|.|.:...:
  Fly    93 KATFSGYDYVILLGMLVISLGIGIFYGFFQKGGSSSNEFLLGSEMSIFPVTLSLTTSFITAIELL 157

Human    67 GLAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRSGVYTMPEYLSKRFGGHRIQVYFAALSL 131
            |........|..........::::.:...:|.|||.:..:.:..|||..|| |..|::..|.|.:
  Fly   158 GNPSEMYFQGTQFVLIVIPMVIVIPVAVKIFYPIYFKMELTSCYEYLGIRF-GKEIRILGAVLYV 221

Human   132 ILYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAVIYTDTLQALLMIIGA 196
            |...| ..:|.:.:.|:.:.::.|.:..::|:|:..:....:..||:.||:..|:.||     ..
  Fly   222 IQMCF-YTAVAVLAPAIALSKATGLDTKIAVVLIYVVCVFYSSQGGMKAVVIADSFQA-----AV 280

Human   197 LTLMIISIMEIGGFEEVKRRYMLASPDVTSILLTYNLSNTNSCNVSPKKEALKMLRNPTDEDVPW 261
            |.:.::.|:.:|.|..       .:|    |.:....|:.|      :.|...|..:||.....|
  Fly   281 LAVSLVLIVGLGCFYS-------GNP----IQVFQTASDHN------RLEFFNMDPDPTTRHTVW 328

Human   262 PGFILGQTPASVWYW----CADQVIVQRVLAAKNIAHAKGSTLMAGF--LKLLPMFII-VVPGMI 319
            ...|.|     .:||    |.:|..||:.::.|::..||   :..||  :.|:.:|:: ...|:
  Fly   329 SVVIGG-----FFYWTSLFCTNQASVQKCMSLKSLRLAK---IALGFAIIGLIVVFLLNFYTGL- 384

Human   320 SRILFTDDIACINPEHCMLVCGSRAGCSNIAYPRLVMKLVP--VGLRGLMMAVMIAALMSDLDSI 382
              ::||....| :|    |..| |...::...|..|:....  ..:.|:.:|.:.||.:..:.|.
  Fly   385 --MVFTHYADC-DP----LTAG-RISATDQLLPYYVINTYEHISSVAGIFVAGIFAASLGTVASA 441

Human   383 FNSASTIFTLDVYKLI---------RKSASSRELMIVGRIFVAFMVVISIAWVPIIVEMQGG--Q 436
            .||.|.:...|:  |:         .|.|:..:.|.:|....:|.:|       .|||..||  |
  Fly   442 LNSLSAVTCEDL--LVNGMNIKISPEKGATYAKWMSLGFGIASFGLV-------FIVEHLGGVLQ 497

Human   437 MYLYIQEVADYLTPPVAALFLLAIFWKRCNEQGAFYGGMAGFVL----GAVRLILAFAYRAPECD 497
            ..|.:..:...:|   ..||:|.|..|:.|.:||||||:....|    |.|..|::       .:
  Fly   498 ATLTLNGLIGGVT---LGLFVLGIACKQANTKGAFYGGLLSLALVIFVGVVAQIVS-------VE 552

Human   498 QPDNRPGFIK-DIHYMYVATGLFWVTGLITVIVSLLTPP 535
            ||.......| |.|           ..:..:|.||||.|
  Fly   553 QPALPTSIDKCDCH-----------VNMTNIIGSLLTEP 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC5A3	NP_008864.4	SLC5sbd_SMIT	9..718	CDD:271382	132/552 (24%)
CG5687	NP_001286910.1	SLC5sbd_NIS-SMVT	99..620	CDD:271383	132/553 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810