Protein Alignment SLC5A3 and CG31262

DIOPT Version :9

• Sequence 1: NP_008864.4
• Gene: SLC5A3 / 6526
• HGNCID: 11038
• Length: 718
• Species: Homo sapiens
• Sequence 2: NP_001138069.2
• Gene: CG31262 / 318649
• FlyBaseID: FBgn0051262
• Length: 579
• Species: Drosophila melanogaster
• Alignment Length: 598
• Identity: 121/598 - (20%)
• Similarity: 233/598 - (38%)
• Gaps: 134/598 - (22%)

Human     7 TADIAIVALYFILVMCIGFF------------AMWKSNRST------VSGYFLAGRSMTWVAIGA 53
            |.|..::....:|....|.:            ::.:.||.|      :..|.:..|:|..:.:..
  Fly     8 TVDYLVLVAMTLLSTGTGIYFGALKKKHKNKKSVSEDNRRTNFGSEKIDEYLMGSRNMKVIPVSI 72

Human    54 SLF--VSNIGSEHFIGLAGSGAASGFAVGAWEFNALLLLQLLG----WVFIPIYIRSGVYTMPEY 112
            :|:  .|.||:...|          :..|...:..::.:.|.|    :|::|:|....:.:..||
  Fly    73 TLYRVTSIIGTPSEI----------YHYGTQYYLIIVAIILQGIAFSYVYLPVYSALQIGSAYEY 127

Human   113 LSKRFGGHRIQVYFAALSLILYIF---TKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTV 174
            |..||..     .....:..:|:|   |.|...:|..||.:.:..|.|.::..:::|......|.
  Fly   128 LGLRFNS-----IIRTTASFMYVFGILTYLPFIVYVPALSLSQVSGLNTHLIGLVIILACVTYTF 187

Human   175 TGGLVAVIYTDTLQALLMIIGALTLMIISIMEIGG----FEEVKR--RYMLASPDVTSILLTYNL 233
            .|||.||::||..|..:|.:..:.:..::|....|    |::.::  |.|||
  Fly   188 MGGLKAVVHTDVWQVAVMFLSLVAVAFLAIYYSNGLVAVFDDAEQGGRLMLA------------- 239

Human   234 SNTNSCNVSPKKEALKMLRNPTDEDVPWPGFILGQTPASVWYW----CADQVIVQRVLAAKNIAH 294
             |||.              :|......|...|.|.:     :|    ...|.:|||.::..::..
  Fly   240 -NTNP--------------SPYVRHTVWSVLIGGFS-----FWTSVNAGGQHMVQRYMSLPSLKK 284

Human   295 AKGSTLMAGFLKLLPMFI-IVVPGMISRILFTDDIACINPEHCMLVCGSRAGCSNIAYPRLVMKL 358
            ::    .|.|:..:.:.| |.:...:..:||:....| :|....::..     .:...|..|::.
  Fly   285 SR----QASFIFTIGVSIFIALCCFMGLLLFSKYKDC-DPRSAGMILN-----DDQLLPLFVVQS 339

Human   359 VP--VGLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVYK-LIRKSASSRELMIVGRIFVAFMVV 420
            |.  .|:.||.:|.:..|.:|.|.|.||:.|.:|..|:.: ..:...|.|:..|:.:..:.|..:
  Fly   340 VGHIYGMPGLFIAGIFGAGLSSLSSCFNTVSMVFLEDIVRGFFKMEPSERQSTILIKTCIIFQGI 404

Human   421 ISIAWVPIIVEMQGGQMYLYIQEVADYLTPPVA----ALFLLAIFWKRCNEQGAFYGG-----MA 476
            ::...|.::..::|      |..|.:.::...|    .:|.|.:.:...|..|...||     :|
  Fly   405 LAFLIVFLLQHLRG------ILSVCNSISSITAGTSFGVFTLGMLFPWANTIGTAVGGLSSVLLA 463

Human   477 GFVLGAVRLILA--------FAYRAPEC----DQPDNRPGFIKDIHYMYVATGLFWVT--GLITV 527
            |::....::..|        ......||    ..|:: |...:|..:........||:  |::|.
  Fly   464 GWISFGSQIAAASGQLKSGMLPVSVKECVGNVTLPED-PWVDQDQVFPLYRLSYHWVSPIGVVTA 527

Human   528 I-----VSLLTPP 535
            :     |||:|.|
  Fly   528 VVVGALVSLITKP 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC5A3	NP_008864.4	SLC5sbd_SMIT	9..718	CDD:271382	120/596 (20%)
CG31262	NP_001138069.2	SLC5sbd_NIS-SMVT	9..522	CDD:271383	113/577 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146453
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243316at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750