Protein Alignment SLC5A1 and CG6723

DIOPT Version :9

• Sequence 1: NP_000334.1
• Gene: SLC5A1 / 6523
• HGNCID: 11036
• Length: 664
• Species: Homo sapiens
• Sequence 2: NP_650069.2
• Gene: CG6723 / 41368
• FlyBaseID: FBgn0037895
• Length: 587
• Species: Drosophila melanogaster
• Alignment Length: 486
• Identity: 112/486 - (23%)
• Similarity: 208/486 - (42%)
• Gaps: 52/486 - (10%)

Human    21 ELIRNA-ADISIIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHF 84
            ||.|.| .|....|..|::.:.:|::..|.....:...:.|.||.|:..||..||.||.:.....
  Fly    10 ELQRFAWPDYVAFVSMFLLCIGIGIYFGFMNKSVSEDDYMLGGRKMLVIPIAFSLVASFVSGITL 74

Human    85 VGLAGTGAASGIAIGGFEWNALVLVVVLGWLFVPIYIKAGVVTMPEYLRKRFGGQRIQVYLSLLS 149
            :||.....:.||.........:.:.||:|..::|::....:.:..|||..|| .:|:::|.|::.
  Fly    75 LGLPTEVYSYGIQYLYVSCGVIGMGVVMGVFYLPVFHDLNITSTYEYLEVRF-DRRLRLYGSVMF 138

Human   150 LLLYIFTKISADIFSGAIFINLALGLNLYLAIFLLLAITALYTITGGLAAVIYTDTLQTVIMLVG 214
            .::.: ..:...|:..|:..|...|:.::....::..|...||..|||.||::||.:|.:.|| |
  Fly   139 AIMNV-AYLPIVIYVPALAFNQVTGIGVHTITPIVCIICVFYTSLGGLKAVVWTDVVQAISML-G 201

Human   215 SLILTGF-AFHEVGGYDAFMEKYMKAIPTIVSDGNTTFQEKCYTPRADSFHIFRDPLTGDLPWPG 278
            :|.|... ...::||....:|:...      ||            |.::..:..||......|..
  Fly   202 ALCLVAIKGTRDIGGAGVVLERAWS------SD------------RLEAPDLSIDPTVRHTFWCL 248

Human   279 FIFGMSILTLWYW----CTDQVIVQRCLSAKNMSHV-KGGCILC-GYLKLMPMFIMVMPGMISRI 337
            |..|     :.||    ...|.::||.||..::... |..||.| |.|     .:|.:.|....:
  Fly   249 FFGG-----IVYWTQTNAVSQNMIQRYLSLPSLGDARKALCIFCVGVL-----ILMALCGYNGLL 303

Human   338 LYTEKIACVVPSECEKYCGTKVGCTNIAYPTLVVELMPN--GLRGLMLSVMLASLMSSLTSIFNS 400
            :|      .....|:..........:...|..|::.:..  |:.||.::.:.::.:|||::..||
  Fly   304 IY------ATYQNCDPLTTKLAKARDQLLPLFVMKTLGELPGMTGLFIAGVFSAALSSLSTCLNS 362

Human   401 ASTLFTMD-IYAKVRKRASEKELMIAGRLFILVLIGISIAWVPIVQSAQ-SGQLFDYIQSITSYL 463
            .|.:...| :...|:|..|...:   ..:..||::|:.:..|.:|...: .|.:.....|:.:..
  Fly   363 MSAVVLEDFVKPYVKKPLSSSAI---NWIMRLVVVGVGVLCVCLVYVVEHMGTVLQLTMSLEAIT 424

Human   464 GPPIAAVFLLAIFWKRVNEPGAFWGLILGLL 494
            ..|:..:|.:.:|...:|...|..|.::|::
  Fly   425 NGPLFGIFTIGLFLPWINGNSALVGGVMGVI 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC5A1	NP_000334.1	SLC5sbd_SGLT1	27..664	CDD:271379	108/479 (23%)
CG6723	NP_650069.2	SLC5sbd_NIS-SMVT	17..537	CDD:271383	108/479 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146494
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740