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Protein Alignment SLC2A4 and CG8837

DIOPT Version :10

Sequence 1:	NP_001033.1	Gene:	SLC2A4 / 6517	HGNCID:	11009	Length:	509	Species:	Homo sapiens
Sequence 2:	NP_608764.1	Gene:	CG8837 / 33545	FlyBaseID:	FBgn0031520	Length:	485	Species:	Drosophila melanogaster

Alignment Length:	521	Identity:	122/521 - (23%)
Similarity:	206/521 - (39%)	Gaps:	107/521 - (20%)

- Green bases have known domain annotations that are detailed below.

Human    18 QRVTGTLVLAVFSAVLGSL---QFGYNIGVINAPQKVIEQSYNETWLGRQGPEGPSSIPPGT--L 77
            :||.|..:.:|.:| ||::   .||...|:..|...:.|..       .:.|...::.|.||  |
  Fly     5 KRVGGPAIQSVATA-LGNILCFNFGLMFGITPAHMTLYESE-------ERTPLNQATDPAGTAWL 61

Human    78 TTLWALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEM--LIL 140
            |....||.|:   |.::|.||    :..:|.|..:|.:.:|.:.|.:.:..     .|::  :..
  Fly    62 TGYLFLSAAL---GALVSGFL----ALKIGPKSVLLCSGLLQISGWACIHF-----GYDIVHIYA 114

Human   141 GRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLN-QLAIVIGILIAQVLG------LESLLGT 198
            .|...|..||....::|:::.|||.:..:.|..|.. :|...:||||..|||      ..:::|.
  Fly   115 SRLFAGVASGAAFVVLPIFINEIAESREKAARLTFTIELWRTLGILIGFVLGFYVPYAFVNIVGC 179

Human   199 ASLWPLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPARKSLKRLTGWADVSGVLAELKDE 263
            |            .:.:..:..||..|||.| |:.:|......|||:...|..|:.
  Fly   180 A------------VSFVFTMTFPFVQESPHY-YLRKNNMASLEKSLRWYRGIRDID--------- 222

Human   264 KRKLERERPLSLLQL-------------LGSRTHRQPLII-----AVVLQLSQQLSGINAVFYYS 310
                :||:|..|.:|             :||.......||     :.:|.:..:|||:.....|:
  Fly   223 ----DREKPEYLSELNEFHAELRSRDKNVGSTPMSHGYIIRLTFVSFLLTVCAKLSGVFVELNYA 283

Human   311 TSIFETAGVGQPAYATIGAGVVNTVFTLVSVLLVERAGRRTLH--LLGLAGMCGCAILMTVAL-- 371
            ...     :|:..|:|....||.........||....|.|...  ||.|:.:...|.::.:||
  Fly   284 ADF-----LGRTGYSTETNYVVLASAQCAGALLARLVGPRLPRKLLLCLSSLFAAAAVIALALFK 343

Human   372 ----LLLERVPAMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTSNF 432
                |.|....|..|:.|:.:...:|....|..|:...:.:|:..........::|...:|...|
  Fly   344 AYGHLWLLGNWADRYLPIILLAIQLALVSFGLYPLAAVVSSEVLPTKLHDLLYSLASAVSWLLLF 408

Human   433 IIGMGFQYVAEAMGPYVFLLFAVLLLGFFIFTFL----RVPETRGRTFDQISAAFHRTPSLLEQE 493
            .:...|..|...:.|.: ||:..:..|..||..|    .:||||           :|.||.:::|
  Fly   409 GMIEAFNAVKATIAPGL-LLYLWVFAGASIFVGLISLPLLPETR-----------NRRPSAVQRE 461

Human   494 V 494
            :
  Fly   462 L 462

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.