Protein Alignment SLC2A3 and CG17929

DIOPT Version :9

• Sequence 1: NP_008862.1
• Gene: SLC2A3 / 6515
• HGNCID: 11007
• Length: 496
• Species: Homo sapiens
• Sequence 2: NP_650532.2
• Gene: CG17929 / 41978
• FlyBaseID: FBgn0038415
• Length: 491
• Species: Drosophila melanogaster
• Alignment Length: 486
• Identity: 103/486 - (21%)
• Similarity: 191/486 - (39%)
• Gaps: 106/486 - (21%)

Human    20 GSFQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSLWSLSVAIFSVGGMIGSFSVGLF 84
            |...|.::.|            .|:||    |...::|...| |       .:|.:.|:....|.
  Fly    65 GGMDFAHSAG------------WNQTL----NTTATQVFKCS-W-------FIGVLAGAALASLT 105

Human    85 VNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGLFCGLCTGFVPMYI--GEISP 147
            :....:....::..|:.:||.... .|| ......|:..|.|.|...||.|  ||..|  .|::.
  Fly   106 MTFLPKLPFYVLGGLMQLTGSIIF-TCK-PFDYGCLLAARYVAGAGIGLIT--VPFLIHSAEVAT 166

Human   148 TALRGAFGTLNQLGIVVGILVAQIFGLEFILGSE----ELWPLL-LGFTILPAILQSAALPFCPE 207
            ...||..|::.|.|:.:||.:..|:..:::...|    |:..:: :.|:|:...:.:.::    |
  Fly   167 DNHRGVSGSMEQCGLALGIAIQVIYDTQWVDDKEASVNEVHGIIGIVFSIIGLGMTALSI----E 227

Human   208 SPRFLLINRKEEENAKQILQRLWGT--QDVSQDIQEM-----KDESARMSQEKQVTVLELFRVSS 265
            ||.:.| ..|::|.|::...:|.|:  ..|.|:.:|:     :.:.....||.:::|:...::..
  Fly   228 SPIYYL-RIKQKEKARKCHAKLLGSFNHSVDQEFEEIQLYVAESQKRTFCQELRISVVPFIKLLL 291

Human   266 YRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQE------PIYATIGAGVVNTIFTVVSLF 324
            ||..:..|..|.||:.|             .|.|.:.|      |:  |:. |:|..:..:|:..
  Fly   292 YRGFVAFSFSLPLSESL-------------IKSALLTEGFISCWPV--TVW-GLVRLLGALVAQG 340

Human   325 LVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDN-------------------YNGMSFVCIGAI 370
            .:::.||:.:.::||..||.....|..|.....|                   :.|: |||..::
  Fly   341 FLDKLGRKFVSLVGLLCMAILMLCMAASYANPANALMTYYMYQVWRLGLAFQAFAGL-FVCSSSV 404

Human   371 LVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYLGAYVFIIF 435
            .:..||    |..:..|.|..:.........:.:.|.:....||..        ||..:...|:.
  Fly   405 YLGEAF----PIKVKPFFVGYIIGFEQTIHIINIVGYNKGYENFFY--------HYYLSVGIILL 457

Human   436 TGFLITFLAFTFFKVPETRGRTFEDITRAFE 466
            .|     :.|....:|||:..|..:.|:.|:
  Fly   458 VG-----VVFFGIVIPETKKTTLREATKLFQ 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC2A3	NP_008862.1	MFS_GLUT_Class1	12..456	CDD:340989	100/474 (21%)
		Important for selectivity against fructose. /evidence=ECO:0000269|PubMed:26176916	277..279		0/1 (0%)
		Monosaccharide binding. /evidence=ECO:0000269|PubMed:26176916	280..286		1/5 (20%)
CG17929	NP_650532.2	Sugar_tr	67..482	CDD:278511	101/481 (21%)
		MFS	295..>425	CDD:119392	31/150 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143983
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840