Protein Alignment SLC2A3 and CG14160

DIOPT Version :9

• Sequence 1: NP_008862.1
• Gene: SLC2A3 / 6515
• HGNCID: 11007
• Length: 496
• Species: Homo sapiens
• Sequence 2: NP_648380.2
• Gene: CG14160 / 39177
• FlyBaseID: FBgn0036066
• Length: 483
• Species: Drosophila melanogaster
• Alignment Length: 472
• Identity: 104/472 - (22%)
• Similarity: 194/472 - (41%)
• Gaps: 93/472 - (19%)

Human    66 SVAIFSVG-GMIGSFSV-----GLFVNRFGRRNSMLIVNLLAVTGGCFMGLC--KVAKSVE---- 118
            |.:|..|| ||..::|:     |.|:|.....|.|:...:.|..|.....|.  :|.|:|.
  Fly    31 SASIVFVGCGMRLAWSIFDTPAGKFLNNHNTHNLMMSWFIGAAVGALLAALFVQRVTKNVAYTSS 95

Human   119 ---MLILGRLVIGL---FCGLC------------TGFVPMYIG-EISPTALRGAFGTLNQLGIVV 164
               |:|.|.|.:.|   |...|            |....:..| |::..::||...:..::.:.:
  Fly    96 GFLMIIAGILNVVLPQHFLAACYSSVSVGAAYGLTQIQALVTGSEVAHKSIRGMLLSCEKIFLWL 160

Human   165 GILVAQIF--------------GLEFILGSEELWPLLLGFTILPAILQSAALPFCPESPRFLLIN 215
            |:.: |:|              |.|..:  ::|..::|....|.|::  .||....||| .||::
  Fly   161 GVCM-QVFYTRVWHNLRPLDTQGYEMHI--DQLHGMVLAGLGLGAVI--LALAHRLESP-LLLLH 219

Human   216 RKEEENAKQILQRLWGTQDVSQDIQEMKD----ESA----RMSQEKQVTVLE----LFRVSSYRQ 268
            ::.:....:.|:.|.| |..::.::..:|    .||    |..:|.:.:|.:    ..|:..:.:
  Fly   220 QERDMAVGETLKALHG-QSTTELVRLREDCRQLHSARDWERFVEEPEESVADWRVWARRILPFFK 283

Human   269 PIIISIVLQLSQQLSGINAVFYYST--GIFKDAGVQEPIYATIGAGVVNTIFTVVSLFLVERAGR 331
            .:::.....|:..|| .|..|...:  |:..|...   :|....||::.   :|:..|:|:..||
  Fly   284 VLLLRCFATLAVSLS-YNRAFVVVSWHGLECDMNC---MYWLAFAGLIG---SVLGAFVVDWQGR 341

Human   332 RTLHMIGLGGMAFCSTLMTVSL--------LLKDNYNGMSFVCIGAILVFVAFFEIGPGPIPWFI 388
            |.:..:.|    |.:.::.|.:        .:|.::..::.:.|..:::.......|...:|..:
  Fly   342 RKVCSLSL----FLAGVVIVMVGGVFDHLESVKRSFYDINLLVIALLMLLFEVIVAGGVAVPALV 402

Human   389 -VAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYLGAYVFIIFTG---FLITFLAFTFFK 449
             .||.||...:  |..:||.........:|||..:..||:...||....|   |::....|.|
  Fly   403 YTAEAFSIAHK--ARCLAGILIVEQLLQLGLLLATFEHYITVSVFFFTIGVFSFIVGLTVFMF-- 463

Human   450 VPETRGRTFEDITRAFE 466
            :||||..|..:....|:
  Fly   464 MPETRQLTLYECLLKFK 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC2A3	NP_008862.1	MFS_GLUT_Class1	12..456	CDD:340989	102/460 (22%)
		Important for selectivity against fructose. /evidence=ECO:0000269|PubMed:26176916	277..279		0/1 (0%)
		Monosaccharide binding. /evidence=ECO:0000269|PubMed:26176916	280..286		2/5 (40%)
CG14160	NP_648380.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143959
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840