Protein Alignment SLC2A3 and CG5592

DIOPT Version :9

• Sequence 1: NP_008862.1
• Gene: SLC2A3 / 6515
• HGNCID: 11007
• Length: 496
• Species: Homo sapiens
• Sequence 2: NP_647996.1
• Gene: CG5592 / 38662
• FlyBaseID: FBgn0035645
• Length: 540
• Species: Drosophila melanogaster
• Alignment Length: 489
• Identity: 115/489 - (23%)
• Similarity: 192/489 - (39%)
• Gaps: 104/489 - (21%)

Human    20 GSFQ--FGYN-------TGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSLW--------SLSV 67
            |||:  |.||       |...|.....| ...|..:.|:...|...:.....|        :.||
  Fly    80 GSFENCFMYNVPYDSNATNDANQTRSPI-PCNNGWIYDRKEVPYESIATEYNWVCDKRDFGTYSV 143

Human    68 AIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGLFCG 132
            .::.||.::|....|...:..||..::.:.|..::.|||...:|   |........|.|.||...
  Fly   144 VVYFVGCIVGCLCFGFITDHSGRLPALFLANSCSMIGGCVSVVC---KDFPCFAASRFVAGLSMN 205

Human   133 LCTGFVPMYIGEISPTALRGAFGTLNQLGI----VVGILVAQIFGLEFILGSEEL-WPLLLGFTI 192
            .|  |||:||            .||..:||    :||.|....|   |.||:..| |   |.:.|
  Fly   206 YC--FVPIYI------------LTLENVGIKYRTLVGNLALTFF---FTLGACLLPW---LAYVI 250

Human   193 -----------LPAILQSAALPFCPESPRFLL----INR-----KE--EENAKQILQRLWGTQDV 235
                       ||.:.........||||.:|:    ::|     ||  :.|.|.|.:.:|...
  Fly   251 SNWRHYAMVVALPIVFMILTSLLAPESPSWLMSVGKVDRCIEVMKEAAKANGKIISEEVWSEM-- 313

Human   236 SQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAG 300
             ::..|:|..:.::.  ||.|.|:||:  ::.:.::::|::           |.:.:..:..||.
  Fly   314 -RECYELKFANEQLG--KQYTSLDLFK--TFPRLVVLTILI-----------VTWMTVALAYDAH 362

Human   301 VQ------EPIYATIG-AGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDN 358
            |:      ..|:.|.. :.:|.....:|.:.|::|.||:.: |..:  |..|:.......:||.:
  Fly   363 VRVVEILDTDIFITFSLSSLVEIPAGIVPMLLLDRIGRKPM-MSAV--MLLCAASSLFVGILKGH 424

Human   359 YNGMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSA 423
            :|. |...|.|.......:.:|.   .|  .:|:.....|...:|:..........|..|:..:.
  Fly   425 WNA-STAAIAARFFATMAYNVGQ---QW--ASEILPTVLRGQGLAIINIMGQMGALLSPLVLSTH 483

Human   424 AHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRT 457
            .:|....:|||....:|..|...|  :|||:|.|
  Fly   484 RYYRPLPMFIITLVSVIGALIILF--LPETKGAT 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC2A3	NP_008862.1	MFS_GLUT_Class1	12..456	CDD:340989	113/486 (23%)
		Important for selectivity against fructose. /evidence=ECO:0000269|PubMed:26176916	277..279		0/1 (0%)
		Monosaccharide binding. /evidence=ECO:0000269|PubMed:26176916	280..286		0/5 (0%)
CG5592	NP_647996.1	2A0119	17..519	CDD:273328	115/489 (24%)
		MFS	141..509	CDD:119392	97/419 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910