Protein Alignment SLC2A3 and CG32054

DIOPT Version :9

• Sequence 1: NP_008862.1
• Gene: SLC2A3 / 6515
• HGNCID: 11007
• Length: 496
• Species: Homo sapiens
• Sequence 2: NP_729588.1
• Gene: CG32054 / 326185
• FlyBaseID: FBgn0052054
• Length: 563
• Species: Drosophila melanogaster
• Alignment Length: 529
• Identity: 107/529 - (20%)
• Similarity: 181/529 - (34%)
• Gaps: 166/529 - (31%)

Human    32 NAPEKIIKEFINKTLTDKG--NAPPSEVL-----------LTSLWSL-------------SVAIF 70
            |.|::.|.  :|.:...:.  |.|.|..:           :...||:             :.|.:
  Fly    98 NPPQQTIT--VNNSWYSRNQKNKPQSNAVGAAGLIFVSGGMNIAWSIGFRGVLHYKTTEHNFAAW 160

Human    71 SVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGLFCGLCT 135
            .:||:||:......:|...::..::..:.|.:.||......|  .|.:..:....:.|:..||.
  Fly   161 FIGGIIGAVISWFLINNVAKKYVLIFSSFLVMIGGILTTSTK--NSGDATLAASYLDGIANGLV- 222

Human   136 GFVPM--YIGEISPTALRG---------AFGTLNQLGIVVGILVAQI-----------FGLEFIL 178
             |.|.  ..||:|.:.:||         .||    |||.:.|:....           |..|.:.
  Fly   223 -FAPFMALAGEVSVSYMRGMVSASIEQMCFG----LGIFLQIIYTSTWNSTAYPSYNSFSAENMK 282

Human   179 GSEELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQD-IQEM 242
            |   :..::.||  |..|:.|.   .|.|||..:|....:|:.|...|:||.....::.: .:::
  Fly   283 G---VLSIIYGF--LALIIGSL---LCIESPVIMLAKNNDEQGAIDALRRLQRPYTLTNETFEQL 339

Human   243 KDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAV---------FYYSTGIFKD 298
            .:....::|.|:   |.:.:......|..|.:|.     |.|:||:         |.||  ....
  Fly   340 AEHKKYLAQNKE---LSMGQSIGQALPTFIRLVF-----LRGLNAMSISKFVMIGFVYS--FASP 394

Human   299 AGVQEP-IYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYNGM 362
            .|...| :...||.||...:...::.|.:|..||:...::||   ..||.              |
  Fly   395 YGYVSPSVGWFIGFGVCRWMGNFIATFCMESCGRKKPTLLGL---IVCSV--------------M 442

Human   363 SFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYL 427
            |||..|...:|.    ...|.....:|.|||:                      |:.|.:.:.||
  Fly   443 SFVVAGQFNIFT----YNTGNNIMLLVFELFA----------------------GIAFTATSPYL 481

Human   428 GA---------YVFIIFTGFLITFLAFTFFK---------------------------VPETRGR 456
            ..         ::...|.|.::.||..|..:                           :||||..
  Fly   482 SEAFPLEVKQHFISFTFIGEMLVFLVLTLIRWSSSGGANYFYVMGGLYLFGFFFGLVCLPETRRT 546

Human   457 TFEDITRAF 465
            |..:....|
  Fly   547 TLREAQDKF 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC2A3	NP_008862.1	MFS_GLUT_Class1	12..456	CDD:340989	105/518 (20%)
		Important for selectivity against fructose. /evidence=ECO:0000269|PubMed:26176916	277..279		0/1 (0%)
		Monosaccharide binding. /evidence=ECO:0000269|PubMed:26176916	280..286		2/5 (40%)
CG32054	NP_729588.1	Pro-rich	<7..101	CDD:291893	1/2 (50%)
		MFS	157..539	CDD:119392	92/450 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143958
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840