Protein Alignment SLC2A3 and CG33281

DIOPT Version :9

• Sequence 1: NP_008862.1
• Gene: SLC2A3 / 6515
• HGNCID: 11007
• Length: 496
• Species: Homo sapiens
• Sequence 2: NP_995620.1
• Gene: CG33281 / 2768938
• FlyBaseID: FBgn0053281
• Length: 467
• Species: Drosophila melanogaster
• Alignment Length: 449
• Identity: 117/449 - (26%)
• Similarity: 186/449 - (41%)
• Gaps: 68/449 - (15%)

Human    45 TLTDKGNAPPSEVLLTSLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNS---MLIVNLLAVTGGC 106
            |.||:|            |..|  ...:||::|:|......:|.||:..   |.:.|||...
  Fly    51 TPTDQG------------WVAS--NICLGGLVGTFLFTWLADRIGRKLCLMWMALPNLLGWV--- 98

Human   107 FMGLCKVAKSVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQI 171
               :...|::...||:.|.:.|...|.|...:|:||.|::...:||..|....|....|:::|.:
  Fly    99 ---IIPFARTPMHLIIARFIGGAAGGGCFTVIPIYIAELASDNIRGILGVFLVLTCNFGLVLAFV 160

Human   172 FGLEFILGSEELWPLLLGFTILPAILQSAALPFCPESPRFLL-INRKEEEN-------------A 222
            .|..|...........|.|..:      ....|.||:|:.|. ||:.||..             |
  Fly   161 LGYYFNYAQVSWIVSSLSFVFV------GCFWFMPETPQHLAKINKIEEAEHSLRYYRNIKSNPA 219

Human   223 KQI-------LQRLWGTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQ 280
            |::       ||:|..|:..:.|  .:.|:.|...    ||..: |.....|:..:|.:.|....
  Fly   220 KELSEELQLELQKLKTTEKTTAD--GVDDDDAATG----VTWSD-FAEGKTRKAFLIGLGLISFN 277

Human   281 QLSGINAVFYYSTGIFKDAGVQ-EPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAF 344
            ||.|..|:..|:..||:.||.. .|..|.|..||:..:.|..|..||||.||:.|.::...|:..
  Fly   278 QLCGCFAMLNYTAVIFEQAGSSLPPTVAAIIVGVIQLMGTYASTVLVERLGRKILLLVSAVGIGL 342

Human   345 CSTLM-TVSL--LLKDNYNGMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAG 406
            ..:.| |.|.  :|.......|:|.|......:....:|...:|:.:|:|:..|..|..|:.:..
  Fly   343 GQSAMGTYSYFQMLGCPVASFSWVPIAGFSFMLFLAAVGLLSLPFLVVSEIMPQKIRSTAIMILM 407

Human   407 CSNWTSNFLVGLLFPSAAHYLGAY--VFIIFTGFLITFLAFTFFK--VPETRGRTFEDI 461
            .:.|..:.....|.|.....||.:  ||:..:   ::|||..|..  ||||:|::.:.|
  Fly   408 STLWLISTCAVKLMPVFTESLGMHGTVFMFAS---LSFLAAIFIAIFVPETKGKSVDAI 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC2A3	NP_008862.1	MFS_GLUT_Class1	12..456	CDD:340989	115/442 (26%)
		Important for selectivity against fructose. /evidence=ECO:0000269|PubMed:26176916	277..279		0/1 (0%)
		Monosaccharide binding. /evidence=ECO:0000269|PubMed:26176916	280..286		3/5 (60%)
CG33281	NP_995620.1	MFS	50..452	CDD:119392	111/436 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143941
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.840