Protein Alignment SLC2A2 and CG6484

DIOPT Version :9

• Sequence 1: NP_000331.1
• Gene: SLC2A2 / 6514
• HGNCID: 11006
• Length: 524
• Species: Homo sapiens
• Sequence 2: NP_611234.1
• Gene: CG6484 / 36994
• FlyBaseID: FBgn0034247
• Length: 465
• Species: Drosophila melanogaster
• Alignment Length: 412
• Identity: 146/412 - (35%)
• Similarity: 221/412 - (53%)
• Gaps: 36/412 - (8%)

Human   101 VSSFAVGGMTASFFG-GWLGDTLGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSISGLY 164
            |||....|.|..... |:..|.:||...||......:||.:||.|:|   :..::..||.|.|:.
  Fly    55 VSSLLTLGATVICIPIGFAIDWIGRRPTMLALIPPYMVGWVLMLFAK---NVTMLYFGRFILGMC 116

Human   165 CGLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHILLGLSGVRA 229
            .|......|||..||..|||||.:|:|.||.||:|:|...::|....|...::      |..:..
  Fly   117 GGAFCVTAPMYCTEITATALRGTIGSFFQLLIVSGVLYGYLVGAFLPLLTINI------LCAILP 175

Human   230 ILQSLLLFFCPESPRYLYIKLDEEVKAKQSLKRLRGYD-DVTKDINEMRKEREEASSEQKVSIIQ 293
            ::.:::.||.||||.||.:|...:..|| :|:.|||.| |:..::.|:.:|     |::::.:.|
  Fly   176 VIFAIIHFFMPESPVYLAMKGRNDDAAK-ALQWLRGKDADIDDELKEILEE-----SQKQIDMPQ 234

Human   294 LFTNSSYRQPIL-----VALMLHVAQQFSGINGIFYYSTSIFQTAG--ISKPVYATIGVGAVNMV 351
            :...||.|:||:     :|::|.|.||::|||.:.:||.|||:..|  ||.. .||:.:|...:.
  Fly   235 VNILSSLRRPIVLKGLGIAVLLQVFQQWTGINAVLFYSASIFEDTGSDISGS-DATLIIGVTQVT 298

Human   352 FTAVSVFLVEKAGRRSLFLIGMSGMFVCAIFMSVGLVL-------LNKFSWMSYVSMIAIFLFVS 409
            .|.|:|.:::|||||.|.||....|.|....|.|...|       ::.|.|:. :|.|.||:.
  Fly   299 STLVAVAIIDKAGRRILLLISGVLMAVSTALMGVYFQLKENDPASMDNFGWLP-ISSICIFII-- 360

Human   410 FFEIGPGPIPWFMVAEFFSQGPRPAALAIAAFSNWTCNFIVALCFQYIADFCGP-YVFFLFAGVL 473
            ||.||.||:||.::||.||:..:..|.:||..|||...|:|.|.|..:....|| ..|::|..:.
  Fly   361 FFSIGFGPVPWLVMAELFSEDVKSVAGSIAGTSNWLSAFVVTLLFPILKSSIGPGPTFWIFTAIA 425

Human   474 LAFTLFTFFKVPETKGKSFEEI 495
            :....::.|.|||||||:..||
  Fly   426 VIAFFYSLFFVPETKGKTIIEI 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC2A2	NP_000331.1	Sugar_tr	14..499	CDD:278511	146/412 (35%)
		MFS	98..485	CDD:119392	137/400 (34%)
		Monosaccharide binding. /evidence=ECO:0000250|UniProtKB:P11166	314..320		3/5 (60%)
CG6484	NP_611234.1	Sugar_tr	14..451	CDD:278511	146/412 (35%)
		MFS	14..436	CDD:119392	137/399 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143917
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.850