Protein Alignment TMEM135 and CG31157

DIOPT Version :9

• Sequence 1: NP_075069.3
• Gene: TMEM135 / 65084
• HGNCID: 26167
• Length: 458
• Species: Homo sapiens
• Sequence 2: NP_001097769.2
• Gene: CG31157 / 318608
• FlyBaseID: FBgn0051157
• Length: 387
• Species: Drosophila melanogaster
• Alignment Length: 327
• Identity: 70/327 - (21%)
• Similarity: 134/327 - (40%)
• Gaps: 56/327 - (17%)

Human    22 SCRVSFLQITGGALEESLKIYAPLYLIAAILRKRKLD-YYLHKLLPEILQSASFLTANGALYMAF 85
            ||..:||.........|.|.|:||.|:..|:..|||. ..:..:.....|||||.....|:....
  Fly    27 SCTKAFLWNLYRNHVSSAKYYSPLLLLPLIMNWRKLSKSMVLSVAKNYAQSASFAAWINAITFYL 91

Human    86 FCILRKILGKF-YSWTPGFGAALP---ASYVAILIERKSRRGLLTIYMANL---ATETL---FRM 140
            .|:.|::..:| :.:.|    .||   ||.::.|:..:    :|..::..:   |.|:|   |.:
  Fly    92 MCMGRRLNDRFVFIFIP----FLPCWIASQLSWLMPPQ----VLHFFVTGITPAAMESLMRYFNI 148

Human   141 GVARGTITTLRNGEVLLFCITAAMYMFFFRCKDGLKGFTFSALRFIVGKEEIP--THSFSPEAAY 203
            |:....:     .:.|||.|::.:.:.:.:.:. ..||.|      :....:|  |..::   ..
  Fly   149 GLVHSPM-----AQTLLFMISSVIVLHYQQTRK-YSGFWF------IRPASLPEDTEDWT---IL 198

Human   204 AKVEQKREQHEEKPGRMNMIGLVRKFVDSICKHGPRHRCCKHYEDNCISYCIKGFIRMFSVGYLI 268
            .:|:|...:.....|    |||....::.:.|     |..|.:.....|: :.|:|.:|.|..|:
  Fly   199 KQVQQGIRELRSYLG----IGLAMDLLNPLMK-----RNMKLWRPKMTSF-LAGYIGLFKVVQLL 253

Human   269 QCCLRIPSAFRHLFTQPSRLLSLFYNKENFQLGAFLGSFVSIYKGTSCFLRW--IRNLDDELHAI 331
                    ..:.|....:..|:.|.:..:|.|.:...:|:.....|:..:.|  :.|..||..::
  Fly   254 --------LLKRLNVNQANALASFISGSSFALLSNRLTFMCFAIVTAIQVIWSQVCNTKDEKDSV 310

Human   332 IA 333
            ::
  Fly   311 LS 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TMEM135	NP_075069.3	TMEM135_C_rich	9..142	CDD:292604	34/130 (26%)
		Tim17	249..>338	CDD:280604	17/87 (20%)
CG31157	NP_001097769.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D378483at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010